Compare Prempro vs. Alora

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prempro
(conjugated estrogens / medroxyprogesterone acetate)

Alora
(estradiol patch)

Coming soon.Relieves hot flashes and vaginal dryness due to menopause and strengthens your bones. Alora (estradiol patch) treats symptoms from low estrogen, and it may have fewer side effects than oral estrogen pills.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Prempro
Best available price for 28 (28 tablets of 0.3mg/1.5mg) packages of prempro
Coupons for Alora
Best available price for 8 (8 patches of 0.1mg/day) cartons of alora
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Prempro (conjugated estrogens / medroxyprogesterone acetate)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Alora (estradiol patch)?
Worth itNot sureNot worth it
Side effects
PremproAlora

We haven’t found good data for Prempro side effects.

FDA side effect reports for Prempro »
  • Breast pain 7%
  • Heartburn 8%
  • Stomach pain 3%
  • Weakness 3%
More Alora side effects »
How it works
PremproAlora
Coming soon.Alora (estradiol patch) replaces an estrogen hormone that your body loses during and after menopause. Higher levels of the hormone relieve symptoms of low estrogen, menopause, and prevent bone loss.
Type of medication
PremproAlora
Prescription only
Available as
PremproAlora
  • Pill
  • Patch
Used for
PremproAlora
  • Menopause Moderate To Severe Abnormal Vasomotor Function Menopause Moderate To Severe Vaginal Atrophy Moderate To Severe Vulvar Atrophy Postmenopausal Osteoporosis
  • Treats Hot Flashes Night Sweats And Flushing In Women In Menopause
Risk factors for serious side effects
PremproAlora
    Coming soon.
    • Using estrogen for more than one year
    • Personal or family history of breast cancer
    • Personal or family history of blood clots
    • Smoking
    Detailed Alora (estradiol patch) risks & warnings »
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Weight
    PremproAlora
    No weight related info.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    Upsides and benefits
    PremproAlora
    Coming soon
    • Alora (estradiol patch) replaces estrogen to your whole body and relieves many symptoms due to low estrogen, like hot flashes and vaginal dryness.
    • The patch is good for people who don't want to or can't take daily pills.
    • Can be worn while swimming, bathing, and showering.
    • By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
    • Lowers your risk of fractures by keeping your bones healthy.
    Downsides and risks
    PremproAlora
    Coming soon
    • You need to replace Alora (estradiol patch) twice a week, compared to other patches that are once a week.
    • Patches can fall off.
    • Increases your risk of uterine and breast cancer.
    • Increases your risk of developing blood clots and stroke.
    • Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
    • Can't be used in people with liver problems.
    Tips from our pharmacists for people taking the medication
    PremproAlora
    Coming soon
    • Remove the patch by tearing the package by hand and not with scissors. Never cut the patch.
    • Apply the sticky side of the patch to clean, dry, hairless skin below your belly button on areas as instructed by the manufacturer (never on your breast).
    • Replace the patch twice a week (every 3-4 days) on a different area of the skin to lower the risk of skin irritation.
    • Fold together the sticky sides of used patches before throwing them away to prevent exposing others to the medicine. Don't flush them down the toilet.
    • Can cause nausea, dizziness, bloating, and breast tenderness.
    • Tell your doctor about any unusual vaginal bleeding.
    Learn more
    More about PremproSide effectsReviews & ratingsFDA package insert
    Have you used Prempro (conjugated estrogens / medroxyprogesterone acetate)?
    Worth itNot sureNot worth it
    More about AloraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Alora (estradiol patch)?
    Worth itNot sureNot worth it