Compare Prempro vs. Estring
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Estring (Estradiol Vaginal Ring) is a vaginal ring that may be less of a hassle than estrogen pills, gels, patches, or vaginal creams, but comes with the same side effects.
- Estring (Estradiol Vaginal Ring) relieves vaginal dryness and irritation to make sex more enjoyable.
- Works locally in the vagina and doesn't expose the rest of your body to estrogen like pills do.
- Good option for people who don't want to take oral pills.
- Generally works well with fewer side effects.
- Many women think Estring (Estradiol Vaginal Ring) is easy to insert and comfortable to use.
- In a 12-week study, Estring (Estradiol Vaginal Ring) worked well to improve vaginal problems, reduced pain during urination, and sudden urges to urinate.
- Estring (Estradiol Vaginal Ring) slowly releases estrogen over the 90 days the ring is in place, so you only have to remove and insert a new one every three months.
- Estring (Estradiol Vaginal Ring) may not be the best estrogen product if you have a narrow vagina or frequent vaginal infections.
- The ring can fall out without you noticing it.
- Increases your risk of endometrial (uterine cancer).
- If you have your uterus, you might need to use Estring (Estradiol Vaginal Ring) with another hormone called progestin to lower your risk of uterine cancer.
- Can be expensive since it's only available as a brand name product.
- Menopause - Moderate to severe abnormal vasomotor function Menopause - Moderate to severe vaginal atrophy - Moderate to severe vulvar atrophy Postmenopausal osteoporosis
- In women with an intact uterus; Prophylaxis
- Vaginal dryness and inflammation
- Vaginal ring
- Back Pain6%
- Genital Moniliasis6%
- Upper Respiratory Tract Infection5%
- Vaginal Discomfort/Pain5%
- Abdominal Pain4%
- Endometrial cancer
Using estrogen for more than one year
- Breast cancer
Personal or family history of breast cancer
...and 1 more risk factors
- Increased risk of blood clots and stroke
Personal or family history of blood clots
...and 2 more risk factors
- Increased risk of heart disease
...and 5 more risk factors
- Harm to fetus
Women of childbearing age
- Pancreas swelling (pancreatitis)
High levels of triglycerides