Compare Prempro vs. Vivelle-Dot
Head-to-head comparisons of medication uses, side effects, ratings, and more.
The Vivelle-Dot (Estradiol Patch) needs to be replaced twice a week, but it comes in more strengths than other patches. It may have fewer side effects than oral estrogen pills.
- Comes in 4 different strengths.
- The Vivelle-Dot (Estradiol Patch) replenishes estrogen to your whole body and relieves multiple symptoms due to low estrogen, like hot flashes and vaginal dryness.
- The patch is good for people who don't want to take daily pills.
- Can be worn while swimming, bathing, and showering.
- By using a patch instead of a pill, there's a lower risk of side effects such as blood clots and stroke since lower amounts of estrogen are used in patches.
- Lowers your risk of fractures by keeping your bones healthy. Make sure you also get enough calcium and Vitamin D.
- Improves mood, energy, and mental alertness for some people.
- You need to replace the Vivelle-Dot (Estradiol Patch) twice a week, compared to other patches that are once a week.
- Patch can fall off.
- Increases your risk of uterine and breast cancer.
- If you have your uterus, you have to use the Vivelle-Dot (Estradiol Patch) with another hormone called progestin to lower your risk of uterine cancer.
- Increases your risk of developing blood clots and stroke.
- Can worsen other health conditions, like high cholesterol, asthma, diabetes, fluid retention, and migraines.
- Can't be used in people with liver problems.
- Menopause - Moderate to severe abnormal vasomotor function Menopause - Moderate to severe vaginal atrophy - Moderate to severe vulvar atrophy Postmenopausal osteoporosis
- In women with an intact uterus; Prophylaxis
- Hot flashes and night sweats
- Vaginal dryness and inflammation
- Low estrogen
- Primary ovarian failure
- Prevention of postmenopausal osteoporosis
- Breast tenderness13%
- Back pain11%
- Intermenstrual bleeding11%
- Upper respiratory tract infection5%
- Endometrial cancer
Using estrogen for more than one year
- Breast cancer
Personal or family history of breast cancer
...and 1 more risk factors
- Increased risk of blood clots and stroke
Personal or family history of blood clots
...and 2 more risk factors
- Increased risk of heart disease
...and 5 more risk factors
- Harm to fetus
Women of childbearing age
- Pancreas swelling (pancreatitis)
High levels of triglycerides