Compare Prevacid vs. Tagamet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevacid (lansoprazole)

Prescription or OTC

Tagamet (cimetidine)

Prescription or OTC
Treats heartburn and stomach ulcers.

Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.

4.0/ 5 average rating with 21 reviewsforPrevacid
Treats heartburn.

Tagamet (cimetidine) works well for heartburn, but may have more side effects than other medicines like it.

3.4/ 5 average rating with 632 reviewsforTagamet
Upsides
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
  • Lasts longer than other medicines like it so you may not need to take it as frequently.
  • Affordable as an over-the-counter or generic medicine.
Downsides
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
  • Does not work as fast as antacids like Maalox, Tums, or Rolaids.
  • May not work as well if you have an inflammed esophagus. Your doctor will assess which medicine is best for you.
  • May not be the best option if you are elderly or have kidney or liver problems.
  • Can interfere with how other medicines work.
Used for
Dosage forms
  • Extended release
  • Dissolving tablet extended release
  • Liquid
  • Pill
  • Liquid
Price
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Reviews
21 reviews so far
71%
saidit'sworth it
71%
saiditworked well
19%
saidit'sa big hassle

Have you used Prevacid (lansoprazole)?

Leave a review
632 reviews so far
63%
saidit'sworth it
36%
saiditworked well
12%
saidit'sa big hassle

Have you used Tagamet (cimetidine)?

Leave a review
Side effects
2possible side effects
  • Diarrhea
    4%
  • Abdominal pain
    2%
See more detailed side effects
The Tagamet (cimetidine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Stomach cancer
  • Acute kidney damage
  • Clostridium difficile associated diarrhea (CDAD)
  • Bone fractures
    • High dose Prevacid (lansoprazole)
    • Long-term treatment with Prevacid (lansoprazole)
    • Low bone mineral density
    • Older age
  • Lupus
  • Low vitamin or mineral levels
See more detailed risks and warnings
  • Confusion
    • Elderly
    • Kidney problems
    • Liver problems
    • Dementia
  • Drug interactions
  • Chronic lung problems
    • Asthma
    • COPD
    • Lung problems
  • Clostridium difficile associated diarrhea
    • Taking antibiotics
  • Englarged breasts in men (gynecomastia)
See more detailed risks and warnings