Compare Prevacid vs. Tagamet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevacid
(lansoprazole)

Tagamet
(cimetidine)

Treats heartburn and stomach ulcers. Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.Treats heartburn. Tagamet (cimetidine) works well for heartburn, but may have more side effects than other medicines like it.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.48Prevacid
Reviews for Prevacid
71%
of people (All ages) say Prevacid is worth it
71%
say it works well
19%
say it's a big hassle
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it
Reviews for Tagamet
63%
+8% better vs. Prevacid
36%
+35% better vs. Prevacid
12%
-7% worse vs. Prevacid
632 reviews
Have you used Tagamet (cimetidine)?
Worth itNot sureNot worth it
Side effects
PrevacidTagamet
  • Diarrhea 2%
  • Abdominal pain 1%
More Prevacid side effects »
  • Headache 2%
More Tagamet side effects »
How it works
PrevacidTagamet
Prevacid (lansoprazole) is a proton pump inhibitor (PPI). It lowers the amount of acid in your stomach by blocking the final step of stomach acid production.Tagamet (cimetidine) reduces acid production in your stomach.
Type of medication
PrevacidTagamet
Prescription or OTCPrescription or OTC
Available as
PrevacidTagamet
  • Extended release
  • Dissolving tablet extended release
  • Liquid
  • Pill
  • Liquid
Used for
PrevacidTagamet
Risk factors for serious side effects
PrevacidTagamet
  • High dose Prevacid (lansoprazole)
  • Long-term treatment with Prevacid (lansoprazole)
  • Low bone mineral density
  • Older age
Detailed Prevacid (lansoprazole) risks & warnings »
  • Elderly
  • Kidney problems
  • Liver problems
  • Dementia
  • Asthma
Detailed Tagamet (cimetidine) risks & warnings »
Pregnancy
Price
PrevacidTagamet
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
No price related info.
Interactions
PrevacidTagamet
  • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
No interactions related info.
Kidneys and liver
PrevacidTagamet
  • Prevacid (lansoprazole) can cause acute kidney damage that can occur at any time during treatment. Stop taking Prevacid (lansoprazole) and speak to your doctor immediately if you notice blood in the urine, changes in urine output, swelling of the body, weight gain, fever, or confusion.
  • Tagamet (cimetidine) can cause confusion if you have kidney or liver problems, dementia, or if you are over 60 years old. Talk to your doctor or pharmacist about alternative medicines if you have any of these conditions.
  • May not be the best option if you are elderly or have kidney or liver problems.
Upsides and benefits
PrevacidTagamet
  • Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
  • Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
  • Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
  • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
  • Lasts longer than other medicines like it so you may not need to take it as frequently.
  • Affordable as an over-the-counter or generic medicine.
Downsides and risks
PrevacidTagamet
  • Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
  • May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
  • Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
  • Does not work as fast as antacids like Maalox, Tums, or Rolaids.
  • May not work as well if you have an inflammed esophagus. Your doctor will assess which medicine is best for you.
  • May not be the best option if you are elderly or have kidney or liver problems.
  • Can interfere with how other medicines work.
Tips from our pharmacists for people taking the medication
PrevacidTagamet
  • Take Prevacid (lansoprazole) with a full glass of water before eating.
  • Starts working in 1 to 3 hours. It can take 1 to 4 days to take full effect.
  • Some prescription drugs can interact with Prevacid (lansoprazole), so talk to your doctor or pharmacist about the medicines you are taking.
  • Do not take for more than 14 days, unless directed by your doctor. Speak to your doctor if your symptoms don't go away after 2 weeks.
  • Prevacid (lansoprazole) capsules can be opened and sprinkled on 1 tablespoon of applesauce, cottage cheese, or yogurt. Swallow immediately after. The dissolving tablets shouldn't be swallowed, broken, or chewed.
  • Take 30 minutes before eating for maximum heartburn relief.
  • Talk to your doctor if you don't see any improvement after 2 weeks.
  • Talk to your doctor if you end up using this medicine more than 2 times a week.
  • Let your doctor or pharmacist know about any other medicines or supplements that you are taking because Tagamet (cimetidine) can interfere with how a lot of other medicines work.
Learn more
More about PrevacidSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Prevacid (lansoprazole)?
Worth itNot sureNot worth it
More about TagametSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tagamet (cimetidine)?
Worth itNot sureNot worth it