Compare Prograf vs. Afinitor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Hecoria
(Tacrolimus)

Afinitor
(Everolimus)

Prevents organ transplant rejection. Hecoria (Tacrolimus) is a good medication that prevents rejection of an organ transplant, but there are a lot of rules to follow while taking it.Coming soon.
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Reviews & ratings
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Side effects
PrografAfinitor

The Prograf FDA package insert doesn’t have numbers about how common side effects are.

More about Prograf side effects »

We haven’t found good data for Afinitor side effects.

FDA side effect reports for Afinitor »
How it works
PrografAfinitor
Hecoria (Tacrolimus) is an immunosuppresant that lowers the activity of your immune system, so it doesn't attack the transplanted organ.Coming soon.
Type of medication
PrografAfinitor
Immunosuppressant
Calcineurin inhibitor
Prescription only
Coming soon.
Available as
PrografAfinitor
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
PrografAfinitor
  • Angiomyolipoma of kidney - Tuberous sclerosis syndrome
Risk factors for serious side effects
PrografAfinitor
  • Taking other immunosuppressant drugs
  • Age 60 or older
  • Weak immune system
    • History of heart problems
    • Drug interactions
      • African-American descent
      • Hispanic descent
      • Kidney transplant patients
      • Poor kidney function
      • Taking kidney-damaging drugs
      Detailed Hecoria (Tacrolimus) risks & warnings »
      Coming soon.
      Pregnancy category
      PrografAfinitor
      Alcohol
      No specific alcohol-related info.No specific alcohol-related info.
      Food
      • Immediate-release capsules can be taken with or without food, just be consistent in how you take it. Extended-release capsules should be taken on an empty stomach, 1 hour before or 2 hours after food.
      No specific food-related info.
      Kidneys and liver
      • Comes with potentially serious side effects like kidney damage, seizures, tremor, and hallucinations.
      • Hecoria (Tacrolimus) can increase your risk of diabetes. If you are at risk, you'll need to monitor your blood glucose levels often. There's a higher risk for African-American and Hispanic kidney transplant patients.
      • Kidney damage can occur when Hecoria (Tacrolimus) is used in high doses, especially in patients with impaired kidney function, or with other damaging (nephrotoxic) drugs like Sirolimus, Cyclosporine.
      No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.No specific sleep-related info.
      Weight
      • Hecoria (Tacrolimus) can increase your risk of serious or life-threatening bacterial, fungal, and viral infections. In some cases, infections can be reactivated from an inactive virus in your body like tuberculosis (TB) or hepatitis B virus (HBV). If you develop symptoms of fever, chills, muscle aches, or you notice dark urine, appetite/weight loss, vomiting, or a skin rash, tell your doctor and get medical care right away.
      No specific weight-related info.
      Upsides and benefits
      PrografAfinitor
      • 96% of patients using Hecoria (Tacrolimus) maintained healthy organ transplants.
      • Can be taken by mouth within 24 hours of a transplant, helping reduce the complications of a lengthy hospital stay.
      • Patients taking Hecoria (Tacrolimus) had fewer heart problems than those taking similar medications.
      • Comes as an extended-release capsule, so it can be taken just once a day.
      • Hecoria (Tacrolimus) doesn't cause hirsutism (unexpected hair growth) or gum overgrowth like Cyclosporine.
      Coming soon.
      Downsides and risks
      PrografAfinitor
      • Regular blood tests are needed, especially in the beginning, to make sure Hecoria (Tacrolimus) isn't affecting your body in a bad way.
      • 20% of patients need insulin to control their blood sugar while taking Hecoria (Tacrolimus).
      • Comes with potentially serious side effects like kidney damage, seizures, tremor, and hallucinations.
      • You'll likely need to take corticosteroids with Hecoria (Tacrolimus).
      • Similar immunosuppressant medications can have fewer side effects.
      • Hecoria (Tacrolimus), like all immunosuppressants increases your risk of infection and certain cancers.
      Coming soon.
      Tips from our pharmacists for people taking the medication
      PrografAfinitor
      • Immediate-release capsules can be taken with or without food, just be consistent in how you take it. Extended-release capsules should be taken on an empty stomach, 1 hour before or 2 hours after food.
      • When getting a transplant, you'll be given several medications. To reduce side effects and interactions, be sure to tell your doctor about any other medications or vitamins you're taking.
      • Hecoria (Tacrolimus) and other immunosuppressants can lower your body's ability to fight infection. It's important that you practice good hygiene, avoid close contact with people who are sick, wear gloves when you garden, keep any cuts clean and covered, and avoid sharing towels or sponges.
      • Don't be out in the sun for too long since you're more likely to get sunburned and increase the risk of skin cancer. Wear protective clothing and sunblock if you have to be out.
      • Let your doctor know about any flu-like symptoms, muscle weakness or cramps, irregular heart beat, changes in eyesight, or if you're not urinating like you normally do.
      Coming soon.
      Learn more
      More about PrografSide effectsReviews & ratingsAlternativesFDA package insert
      More about AfinitorSide effectsFDA package insert