Compare Prometrium vs. Danazol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prometrium (Progesterone)

Prescription only
Taken for irregular bleeding or paired with estrogen replacements for menopause.

Prometrium (Progesterone) regulates menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.

4.6/ 7 average rating with 64 reviewsforPrometrium
No information currently available
  • Helps to regulate your menstrual cycle.
  • Relives pain from endometriosis.
  • Lowers the risk of uterine cancer when used with estrogen in women with an intact uterus.
  • Available as a capsule or an injection, so you can choose what works best for you.
No information currently available
  • Prometrium (Progesterone) capsules contain peanut oil, so you can't take it if you're allergic to peanuts.
  • Prometrium (Progesterone) can cause serious birth defects in babies, so you can't take Prometrium (Progesterone) if you’re pregnant or breast-feeding.
  • Increases your risk of blood clots.
No information currently available
Used for
  • Amenorrhea
  • Prevention of uterine cancer in women taking estrogen
  • Abnormal uterine bleeding
  • Endometriosis Fibrocystic breast changes Hereditary angioedema
Dosage forms
  • Pill
  • Injection
  • Pill
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Side effects
The Prometrium (Progesterone) FDA package insert doesn’t have numbers about how common side effects are.
The Danocrine (Danazol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Breast cancer

    Personal or family history of breast cancer

  • Ovarian cancer

    Family history of ovarian cancer

  • Increased risk of blood clots and stroke

    Personal or family history of blood clots

    ...and 6 more risk factors

  • Severe allergic reactions

    Allergy to peanuts

  • Fluid retention (Foot and leg swelling)

    Heart failure

    ...and 2 more risk factors

  • Depression

    History of depression

See more detailed risks and warnings
No information currently available