Compare Propranolol vs. Bystolic

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Inderal (Propranolol)

Prescription only

Bystolic (Nebivolol)

Prescription only
Lowers blood pressure and controls heart rate.

Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.

3.9/ 5 average rating with 61 reviewsforPropranolol
Lowers blood pressure and controls heart rate.

Bystolic (Nebivolol) is a good blood pressure-lowering medicine for people with heart conditions, and has fewer side effects than other beta blockers, but it's expensive. You can't miss doses.

3.6/ 5 average rating with 154 reviewsforBystolic
Upsides
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
  • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
  • Controls your heart rate to reduce work for your heart.
  • A first-line treatment for heart failure and heart attack.
  • Helps to lower blood pressure if you can't use first-choice treatments or need additional blood pressure control.
  • Many beta blockers can worsen asthma or cause headaches, but Bystolic usually doesn't because it targets the heart more specifically and causes fewer side effects.
Downsides
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not available in less expensive generic form.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Bystolic suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Pill
Price
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Reviews
61 reviews so far
66%
saidit'sworth it
62%
saiditworked well
15%
saidit'sa big hassle

Have you used Inderal (Propranolol)?

Leave a review
154 reviews so far
53%
saidit'sworth it
49%
saiditworked well
18%
saidit'sa big hassle

Have you used Bystolic (Nebivolol)?

Leave a review
Side effects
3possible side effects
  • Dizziness
    7%
  • Fatigue
    5%
  • Constipation
    3%
See more detailed side effects
4possible side effects
  • Headache
    9%
  • Diarrhea
    2%
  • Fatigue
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Increased chest pain or risk of heart attack
    • Suddenly stopping Inderal (Propranolol)
  • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
  • Low blood pressure
    • Concurrent use of non-dihydropyridine calcium channel blockers, digoxin or clonidine
  • Serious skin reactions
See more detailed risks and warnings
  • Heart problems
    • Sudden discontinuation of medicine
  • Trouble breathing (bronchospastic disease)
    • History of asthma
  • Low blood sugar unawareness
    • History of diabetes
  • Low heart rate (bradycardia)
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
See more detailed risks and warnings