Compare Propranolol vs. Detrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Inderal
(propranolol)

Detrol
(tolterodine)

Lowers blood pressure and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.Treats overactive bladder. Detrol (tolterodine) is a good treatment for overactive bladder after exercises and other methods to control it haven't worked.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.39Propranolol
Reviews for Propranolol
66%
of people (All ages) say Propranolol is worth it
62%
say it works well
15%
say it's a big hassle
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it

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Have you used Detrol (tolterodine)?
Worth itNot sureNot worth it
Side effects
PropranololDetrol
  • Dizziness 5%
  • Fatigue 2%
  • Constipation 3%
More Propranolol side effects »
  • Dry mouth 25%
  • Headache 2%
  • Constipation 3%
  • Dizziness 2%
  • Stomach pain 2%
  • Tiredness 1%
  • Diarrhea 1%
  • Indigestion 3%
  • Drowsiness 1%
  • Dry eyes 1%
More Detrol side effects »
How it works
PropranololDetrol
Inderal (Propranolol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Detrol (tolterodine) is an antimuscarinic. It helps people control the urge to urinate by relaxing the bladder muscles and stopping them from spasming.
Type of medication
PropranololDetrol
Prescription onlyPrescription only
Available as
PropranololDetrol
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Extended release
Used for
PropranololDetrol
Risk factors for serious side effects
PropranololDetrol
  • Suddenly stopping Inderal (Propranolol)
  • Major surgery requiring anesthesia
  • Diabetes
  • Concurrent use of non-dihydropyridine calcium channel blockers, digoxin or clonidine
Detailed Inderal (propranolol) risks & warnings »
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • People age 65 or older
  • Glaucoma
  • History of bladder problems
Detailed Detrol (tolterodine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
PropranololDetrol
No alcohol related info.
  • Drinks with caffeine, alcohol or carbonation can make your symptoms worse.
Food
PropranololDetrol
No food related info.
  • You can take Detrol (tolterodine) with or without food.
Kidneys and liver
PropranololDetrol
No kidneys and liver related info.
  • If you have liver or kidney problems, talk to your doctor before starting Detrol (tolterodine). You might have to use a lower dose, or you might not be able to take Detrol (tolterodine) at all.
Sleep
PropranololDetrol
No sleep related info.
  • You can get drowsy or dizzy on Detrol (tolterodine). Do not stand or sit up too quickly if you've been sitting or lying down for a while.
  • Detrol (tolterodine) can cause drowsiness, dizziness and can increase your risk for falls.
Upsides and benefits
PropranololDetrol
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
  • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
  • Detrol (tolterodine) is effective at treating overactive bladder by lowering the urge to urinate, and controlling urination.
  • The tablet is available as a generic in both extended and immediate release, so you can take it once or twice a day.
Downsides and risks
PropranololDetrol
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Detrol (tolterodine) can cause drowsiness, dizziness and can increase your risk for falls.
  • Detrol (tolterodine) can cause severe dry mouth and eyes and constipation.
  • Generally not recommended if you are 65 or older.
  • Do not use if you have uncontrolled narrow-angle glaucoma.
Tips from our pharmacists for people taking the medication
PropranololDetrol
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause insomnia and fatigue.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Detrol (tolterodine) can take up to 4 weeks before you notice any changes.
  • Drinks with caffeine, alcohol or carbonation can make your symptoms worse.
  • You can get drowsy or dizzy on Detrol (tolterodine). Do not stand or sit up too quickly if you've been sitting or lying down for a while.
  • You can take Detrol (tolterodine) with or without food.
  • Do not break, crush or chew extended-release capsules.
Learn more
More about PropranololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it
More about DetrolSide effectsAlternativesFDA package insert
Have you used Detrol (tolterodine)?
Worth itNot sureNot worth it