Compare Propranolol vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Inderal
(propranolol)

Lopressor
(metoprolol tartrate)

Lowers blood pressure and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.Lowers blood pressure and controls heart rate. Lopressor (metoprolol tartrate) lowers high blood pressure, controls chest pain, and helps treat heart failure and heart attack. You need to take it with food and can't miss a dose.
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Coupons for Propranolol
Best available price for 60 (20mg) tablets of propranolol
Coupons for Lopressor
Best available price for 60 (25mg) tablets of lopressor
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.39Propranolol
Reviews for Propranolol
66%
of people (All ages) say Propranolol is worth it
62%
say it works well
15%
say it's a big hassle
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it
Reviews for Lopressor
62%
+4% better vs. Propranolol
47%
+15% better vs. Propranolol
15%
Same vs. Propranolol
464 reviews
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it
Side effects
PropranololLopressor
  • Dizziness 5%
  • Fatigue 2%
  • Constipation 3%
More Propranolol side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching or skin rash 5%
  • Shortness of breath 3%
  • Slowed heart rate 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
PropranololLopressor
Inderal (Propranolol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Lopressor (metoprolol tartrate) is a beta blocker. It lowers blood pressure by slowing your heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
PropranololLopressor
Prescription onlyPrescription only
Available as
PropranololLopressor
  • Pill
  • Extended release
  • Liquid
  • Pill
Used for
PropranololLopressor
Risk factors for serious side effects
PropranololLopressor
  • Suddenly stopping Inderal (Propranolol)
  • Major surgery requiring anesthesia
  • Diabetes
  • Concurrent use of non-dihydropyridine calcium channel blockers, digoxin or clonidine
Detailed Inderal (propranolol) risks & warnings »
  • Suddenly stopping Lopressor (metoprolol tartrate)
  • Coronary artery disease
  • Diabetes
  • Heart failure
  • Major surgery requiring anesthesia
Detailed Lopressor (metoprolol tartrate) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
PropranololLopressor
No food related info.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
Pain
PropranololLopressor
No pain related info.
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
Upsides and benefits
PropranololLopressor
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
  • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
  • A first-choice treatment to prevent chest pain (angina).
  • Makes pain episodes less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for people who've had a heart attack.
  • Lopressor (metoprolol tartrate) lowers the risk of death during and after a heart attack.
  • Lopressor (metoprolol tartrate) is cheaper than the extended release version.
Downsides and risks
PropranololLopressor
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • You need to take Lopressor (metoprolol tartrate) with food twice a day for it to work best.
  • Taking Lopressor (metoprolol tartrate) may make you feel more tired or out of breath during exercise or your normal daily routines. This gets better for most people, but for some it may not go away.
  • Not a first-choice treatment for high blood pressure, unless you have heart failure or heart disease. It can also be added to other medicines if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Lopressor (metoprolol tartrate) suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
PropranololLopressor
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause insomnia and fatigue.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • You should take Lopressor (metoprolol tartrate) with or after meals.
  • Lopressor (metoprolol tartrate) can make you feel dizzy for the first few days. It can also cause fatigue and headaches.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly unless your doctor tells you to.
  • This is the immediate release version of the medication, so it needs to be taken twice a day. It's different from the extended release form: Toprol XL (metoprolol succinate).
Learn more
More about PropranololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it
More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lopressor (metoprolol tartrate)?
Worth itNot sureNot worth it