Compare Propranolol vs. Zomig

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Inderal
(propranolol)

Zomig
(zolmitriptan)

Lowers blood pressure and controls heart rate. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. You can't miss doses.Treats migraines. Triptans are the first-choice to treat migraines. Zomig (zolmitriptan) works just as well as other triptans for migraines.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.39Propranolol
Reviews for Propranolol
66%
of people (All ages) say Propranolol is worth it
62%
say it works well
15%
say it's a big hassle
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it

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Have you used Zomig (zolmitriptan)?
Worth itNot sureNot worth it
Side effects
PropranololZomig
  • Dizziness 5%
  • Fatigue 2%
  • Constipation 3%
More Propranolol side effects »
  • Nervous system problems 7%
  • Stomach problems 8%
  • Pain and pressure sensation 7%
  • Unusual sensations 6%
  • Nausea 5%
  • Dizziness 4%
  • Tingling or prickling sensation 5%
  • Neck, throat or jaw pain/pressure 4%
  • Sleepiness 3%
  • Warm or cold sensation 1%
More Zomig side effects »
How it works
PropranololZomig
Inderal (Propranolol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Zomig (zolmitriptan) is a triptan. It prevents the enlargement of blood vessels in your brain, which causes migraines.
Type of medication
PropranololZomig
Prescription onlyPrescription only
Available as
PropranololZomig
  • Pill
  • Extended release
  • Liquid
  • Pill
  • Dissolving tablet
  • Nasal spray
Used for
PropranololZomig
Risk factors for serious side effects
PropranololZomig
  • Suddenly stopping Inderal (Propranolol)
  • Major surgery requiring anesthesia
  • Diabetes
  • Concurrent use of non-dihydropyridine calcium channel blockers, digoxin or clonidine
Detailed Inderal (propranolol) risks & warnings »
  • Heart disease
  • history of chest pain/angina
  • uncontrolled high blood pressure
  • History of a stroke
  • Using Zomig (zolmitriptan) or other migraine treatment medications for 10 or more days a month
Detailed Zomig (zolmitriptan) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Upsides and benefits
PropranololZomig
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure, heart attack, heart valve disorders, and abnormal heart rhythm.
  • Also treats and prevents many non-heart problems, such as tremors, anxiety, migraines, and liver disease symptoms.
  • Zomig (zolmitriptan) is is a first choice treatment to treat severe migraines.
  • There are different forms of Zomig (zolmitriptan) available, including a dissolving pill and a nasal spray if you have trouble swallowing during a migraine attack.
  • The regular and dissolving pill forms of Zomig (zolmitriptan) are available as generics.
Downsides and risks
PropranololZomig
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Has more side effects than some beta blockers because it crosses into the brain and central nervous system.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Propranolol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • If you're taking the nasal spray form of Zomig (zolmitriptan), you have to follow the instructions exactly or you won't get the full dose of medicine.
  • The nasal spray form of Zomig (zolmitriptan) is only available as brand name, so it can be expensive.
  • If you have heart disease or history of stroke, Zomig (zolmitriptan) may not be the best choice for you. Talk to your doctor about your medical history.
Tips from our pharmacists for people taking the medication
PropranololZomig
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can cause insomnia and fatigue.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Doesn't prevent migraines.
  • Use as soon as you feel a migraine starting. You can take another dose 2 hours later, but don't take more than 10 mg total in 24 hours.
  • Don't use it excessively since it can cause you to have more headaches. Talk to your doctor if you are having more than 4 migraines in a month.
Learn more
More about PropranololSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Inderal (propranolol)?
Worth itNot sureNot worth it
More about ZomigSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zomig (zolmitriptan)?
Worth itNot sureNot worth it