Compare Estazolam vs. Ambien

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prosom
(estazolam)

Ambien
(zolpidem)

Helps you stay asleep longer. Prosom (estazolam) can help you sleep, but you might feel hungover the next day.Helps you sleep. Ambien (zolpidem) aids in falling asleep and staying asleep, but it can be habit-forming and might be more likely than other sleep medicines to cause side effects.
Reviews & ratings
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Have you used Prosom (estazolam)?
Worth itNot sureNot worth it
Reviews for Ambien
67%
-67% worse vs. Estazolam
50%
-50% worse vs. Estazolam
16%
+16% better vs. Estazolam
1375 reviews
Have you used Ambien (zolpidem)?
Worth itNot sureNot worth it
Side effects
EstazolamAmbien
  • Sleepiness 15%
  • Weakness 3%
  • Difficulty controlling muscles 4%
  • Dizziness 4%
  • Abnormal coordination 3%
  • Leg and foot pain 1%
More Estazolam side effects »
  • Drowsiness 3%
  • Headache 1%
  • Dizziness 4%
  • Allergic reactions 3%
  • Sinus infection 2%
  • Sore throat 2%
  • Dry mouth 2%
  • Lack of energy 2%
  • Back pain 1%
  • Diarrhea 1%
More Ambien side effects »
How it works
EstazolamAmbien
Prosom (estazolam) is a benzodiazepine. It helps you stay asleep by improving the quality of your sleep so you don't wake up as much at night.Ambien (zolpidem) is in a class of drugs called sedative-hypnotics. It interacts with your brain to make you relaxed and sleepy.
Type of medication
EstazolamAmbien
Prescription onlyPrescription only
Available as
EstazolamAmbien
  • Pill
  • Pill
  • Oral spray
  • Sublingual pill
Used for
EstazolamAmbien
Risk factors for serious side effects
EstazolamAmbien
  • Using Prosom (estazolam) for more than 10 days
  • Drinking alcohol
  • Taking sedative medicines
  • People age 65 or older
Detailed Prosom (estazolam) risks & warnings »
  • Continuous use of Ambien (zolpidem) for 2 weeks or more
  • Alcohol
  • Taking other medications that make you less alert
  • Less than 8 hours of sleep.
  • Undiagnosed psychiatric conditions
Detailed Ambien (zolpidem) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Alcohol
EstazolamAmbien
  • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
  • Avoid alcohol and drugs when taking Ambien (zolpidem).
Kidneys and liver
EstazolamAmbien
No kidneys and liver related info.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
Sleep
EstazolamAmbien
No sleep related info.
  • Ambien (zolpidem) makes you feel drowsy and sleepy, potentially leading to falls and severe injuries. This is especially a risk if you're older. Falls from sleep medicines like Ambien (zolpidem) have caused severe injuries such as hip fractures and head injury. You may need a lower dose if you're taking other medications that also cause drowsiness. Check with your doctor first.
  • Only take it if you have time to sleep for at least 8 hours.
  • Effective at helping people fall asleep faster and sleep longer.
Upsides and benefits
EstazolamAmbien
  • Prosom (estazolam) is available in generic.
  • Effective at helping people fall asleep faster and sleep longer.
  • Extended release form is particularly good for staying asleep, and you can use it for longer than the immediate release form.
  • Generic is available.
Downsides and risks
EstazolamAmbien
  • Prosom (estazolam) isn't recommended if you're age 65 or older because the side effects can be more intense.
  • You can become dependent on Prosom (estazolam) if you take it for more than a few weeks.
  • If you stop Prosom (estazolam) suddenly after taking it for a while, your insomnia might come back even worse than when you started.
  • Not typically used for long-term treatment because it can be habit-forming.
  • Some people find that Ambien (zolpidem) becomes less effective over time.
  • More likely to cause sleep-walking, sleep-driving, and sleep-eating.
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
Tips from our pharmacists for people taking the medication
EstazolamAmbien
  • Don't take Prosom (estazolam) unless you know you'll be going to sleep right away.
  • Make sure you can sleep for at least 8 hours before you take it.
  • Prosom (estazolam) works best if you develop good sleeping habits.
  • Take Prosom (estazolam) for the shortest amount of time needed to treat your insomnia since it can be addicting.
  • Don't drink alcohol or take other narcotics with Prosom (estazolam) because it can slow your breathing.
  • Take 30 to 45 minutes before bedtime.
  • Only take it if you have time to sleep for at least 8 hours.
  • Can be addictive. Meant for short-term treatment. Dependence can form after daily use for 2 weeks.
  • Avoid alcohol and drugs when taking Ambien (zolpidem).
  • Withdrawal symptoms can occur if you abruptly stop the drug and you've been regularly using it. The symptoms usually resolve in 1 to 2 nights.
  • Report any confusion or changes in thoughts or behavior.
Learn more
More about EstazolamSide effectsAlternativesFDA package insert
Have you used Prosom (estazolam)?
Worth itNot sureNot worth it
More about AmbienSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ambien (zolpidem)?
Worth itNot sureNot worth it