Compare Provigil vs. Kapvay

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Provigil
(modafinil)

Kapvay
(clonidine)

Improves alertness. Provigil (Modafinil) is effective in improving alertness, but it can interact with other medicines and shouldn't be used long-term.Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.
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Coupons for Provigil
Best available price for 30 (200mg) tablets of provigil
Coupons for Kapvay
Best available price for 60 (0.1mg) tablets of clonidine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.75Provigil
Reviews for Provigil
82%
of people (All ages) say Provigil is worth it
71%
say it works well
4%
say it's a big hassle
Have you used Provigil (modafinil)?
Worth itNot sureNot worth it

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Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it
Side effects
ProvigilKapvay
  • Headache 11%
  • Nausea 8%
  • Any side effect 5%
  • Inflammation inside the nose 1%
  • Nervousness 4%
  • Back pain 1%
  • Diarrhea 1%
  • Dizziness 1%
  • Sleep difficulty 4%
  • Indigestion 1%
More Provigil side effects »
  • Drowsiness 34%
  • Headache 4%
  • Fatigue 15%
  • Upper abdominal pain 3%
  • Irritability 5%
  • Any side effect 6%
  • Dizziness 2%
  • Sleep difficulty 4%
  • Nausea 1%
  • Emotional disorder 3%
More Kapvay side effects »
How it works
ProvigilKapvay
Provigil (Modafinil) is a stimulant that helps you feel awake. Researchers don't know exactly how Provigil (Modafinil) works, but it probably affects chemicals (neurotransmitters) in the brain.Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.
Type of medication
ProvigilKapvay
Prescription onlyPrescription only
Available as
ProvigilKapvay
  • Pill
  • Extended release
Used for
ProvigilKapvay
Risk factors for serious side effects
ProvigilKapvay
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Current kidney problems
  • Current liver problems
  • History of heart problems
Detailed Provigil (modafinil) risks & warnings »
  • Sudden discontinuation of medicine
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 years or older
  • Using other medicine(s) that slows the heart
Detailed Kapvay (clonidine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
ProvigilKapvay
  • Interacts with many other medications.
No interactions related info.
Alcohol
ProvigilKapvay
  • Don't drink alcohol with Provigil (Modafinil).
No alcohol related info.
Kidneys and liver
ProvigilKapvay
  • Not a good choice if you have liver or kidney problems.
  • Provigil (Modafinil) is broken down by the kidney and liver. If you have kidney or liver problems, you may need to use a lower dose to prevent more side effects.
No kidneys and liver related info.
Sleep
ProvigilKapvay
No sleep related info.
  • Can cause drowsiness, headache, dizziness, and dry mouth.
Upsides and benefits
ProvigilKapvay
  • It's a non-amphetamine medicine that helps improve alertness.
  • Available in a generic version.
  • Effective in reducing excessive sleepiness in Shift-work Sleep Disorder.
  • Doesn't negatively affect daytime sleep.
  • Can be used alone or together with a stimulant-type medicine to treat ADHD.
  • In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
  • Also treats blood pressure and some nervous system and psychiatric conditions.
Downsides and risks
ProvigilKapvay
  • Provigil (Modafinil) can be habit-forming, so it's typically not used for long-term treatment.
  • Interacts with many other medications.
  • Taking Provigil (Modafinil) will make hormonal birth control less effective. You should definitely use additional forms of non-hormonal contraception.
  • Not a good choice if you have liver or kidney problems.
  • Can lower blood pressure.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
ProvigilKapvay
  • Take Provigil (Modafinil) about an hour before you need to be fully alert.
  • Taking caffeine with Provigil (Modafinil) can cause you to feel nervous, shaky, and have a faster heartbeat. Try limiting your caffeine intake.
  • Until you know how Provigil (Modafinil) makes you feel, don't drive or perform any tasks that need you to be alert.
  • You can experience withdrawal symptoms if you suddenly stop taking Provigil (Modafinil). Talk to your doctor before making any changes.
  • Tell your doctor right away if you break out in a rash.
  • Don't drink alcohol with Provigil (Modafinil).
  • Can cause drowsiness, headache, dizziness, and dry mouth.
  • For ADHD: Might take up to 2 weeks to see effects.
  • For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • If side effects don't go away, talk to your doctor about alternatives.
  • Don't stop taking this medicine suddenly.
Learn more
More about ProvigilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Provigil (modafinil)?
Worth itNot sureNot worth it
More about KapvaySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Kapvay (clonidine)?
Worth itNot sureNot worth it