Compare Prozac vs. Klonopin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prozac (Fluoxetine)

Prescription only

Klonopin (Clonazepam)

Prescription only
Improves mood and helps you relax.

Prozac (Fluoxetine) is good for treating depression and anxiety. It's more energizing than other antidepressants, but may not be the best choice for people who have trouble sleeping.

4.7/ 7 average rating with 1319 reviewsforProzac
Controls seizures and helps you relax.

Klonopin (Clonazepam) is okay for occasional or short-term use (up to 4 weeks) for anxiety, and to treat seizures. Less severe withdrawal symptoms compared to similar drugs.

5.2/ 7 average rating with 767 reviewsforKlonopin
Upsides
  • Effective at relieving depression and anxiety symptoms.
  • Lowers relapse rates of depression and bulimia nervosa.
  • Causes less sleepiness than other antidepressants.
  • It's more energizing than other antidepressants, so it's good for people who have low energy.
  • It has been used to treat depression for a long time, so there's a lot of information available about how it works and how safe it is.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
  • Effective at relieving short-term anxiety and sleeplessness.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in (it can take several weeks).
  • Can be used alone or with other medicines to treat seizures.
  • Less severe withdrawal symptoms compared to other benzodiazepines.
Downsides
  • Can cause sexual side effects like low libido and an inability to orgasm or ejaculate.
  • Can increase feelings of anxiety or cause headaches during the first few weeks of taking it. These effects should go away over time.
  • More likely than other antidepressants to interact with other medications you're taking.
  • Like most antidepressants, it can cause a higher risk of suicidal thoughts and behavior for people younger than 24.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment, or for people who've had problems with drug or alcohol abuse.
  • Most people find that it gets less effective over time.
Used for
Dosage forms
  • Pill
  • Delayed release capsule
  • Liquid
  • Pill
  • Dissolving tablet
Price
Lowest price near you
$4
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Lowest price near you
$7.39
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Reviews
1319 
62%
think this treatment is worth it
40%
think this treatment works well
16%
think this treatment is a hassle

Have you used Prozac (Fluoxetine)?

Leave a review
767 
70%
think this treatment is worth it
52%
think this treatment works well
14%
think this treatment is a hassle

Have you used Klonopin (Clonazepam)?

Leave a review
Side effects
1possible side effects
  • Decreased libido
    4%
See more detailed side effects
10possible side effects
  • Somnolence
    37%
  • Dizziness
    8%
  • Upper Respiratory Tract Infection
    8%
  • Depression
    7%
  • Fatigue
    7%
  • Coordination Abnormal
    6%
  • Ataxia
    5%
  • Memory Disturbance
    4%
  • Sinusitis
    4%
  • Influenza
    4%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Using other medications that affect serotonin

  • Withdrawal

    Stopping Prozac (Fluoxetine) suddenly

  • Heart problems

    History of heart problems

    ...and 2 more risk factors

  • Increased bleeding

    Taking other blood-thinning drugs

  • Mania

    History of bipolar disorder

    ...and 1 more risk factors

See more detailed risks and warnings
  • Tolerance and dependence

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Withdrawal

    Long-term use

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings