Compare Relafen vs. Tylenol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relafen
(nabumetone)

Tylenol Regular Strength
(acetaminophen)

Coming soon.Relieves pain and fever. Tylenol Regular Strength (acetaminophen) effectively reduces fever and relieves pain, but it doesn't lower inflammation and swelling.
Reviews & ratings
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Have you used Relafen (nabumetone)?
Worth itNot sureNot worth it
Reviews for Tylenol
77%
-44% worse vs. Relafen
37%
-4% worse vs. Relafen
3%
+3% better vs. Relafen
1002 reviews
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it
Side effects
RelafenTylenol

We haven’t found good data for Relafen side effects.

FDA side effect reports for Relafen »

The Tylenol FDA package insert doesn’t have numbers about how common side effects are.

More about Tylenol side effects »
How it works
RelafenTylenol
Coming soon.Tylenol Regular Strength (acetaminophen) is an analgesic. It relieves pain and lowers fever by stopping the production of certain chemicals in the brain that cause both pain and fever.
Type of medication
RelafenTylenol
Over-the-counter
Available as
RelafenTylenol
  • Pill
  • Pill
  • Chewable tablet
  • Dissolving tablet
  • Liquid
  • Suppository
  • Injection
Used for
RelafenTylenol
  • Osteoarthritis Rheumatoid Arthritis
Risk factors for serious side effects
RelafenTylenol
    Coming soon.
    • Medication administering errors
    • Injection formulation
    • Exceeding the recommended maximum daily limits
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    Detailed Tylenol Regular Strength (acetaminophen) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    RelafenTylenol
    No alcohol related info.
    • Drinking alcohol while taking Tylenol Regular Strength (acetaminophen) can damage your liver.
    • Heavy alcohol drinkers and people with liver problems should avoid using Tylenol Regular Strength (acetaminophen) since it can cause serious liver damage.
    Kidneys and liver
    RelafenTylenol
    No kidneys and liver related info.
    • Taking too much acetaminophen causes liver damage that can be permanent and life-threatening. Signs of liver problems may include dark urine, feeling tired, upset stomach or stomach pain, or yellow skin or eyes. If you notice any of these symptoms, call your doctor immediately. Avoid drinking alcohol when taking Tylenol Regular Strength (acetaminophen). Avoid using Tylenol Regular Strength (acetaminophen) if you have existing liver problems since it can cause further damage.
    • Doesn't cause kidney damage and is also safe to use if you have heart problems or if you're pregnant.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen you are taking since it's a very common ingredient in pain and cold combination medicines.
    Pain
    RelafenTylenol
    No pain related info.
    • Works well to relieve pain and fevers.
    Upsides and benefits
    RelafenTylenol
    Coming soon
    • Works well to relieve pain and fevers.
    • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
    • Tylenol Regular Strength (acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin and Advil.
    • Doesn't cause kidney damage and is also safe to use if you have heart problems or if you're pregnant.
    • Tylenol Regular Strength (acetaminophen) has been used for a long time and is generally safe for short-term use.
    Downsides and risks
    RelafenTylenol
    Coming soon
    • Tylenol Regular Strength (acetaminophen) doesn't treat some kinds of pain as well as other medications like Advil.
    • Drinking alcohol while taking Tylenol Regular Strength (acetaminophen) can damage your liver.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen you are taking since it's a very common ingredient in pain and cold combination medicines.
    • Heavy alcohol drinkers and people with liver problems should avoid using Tylenol Regular Strength (acetaminophen) since it can cause serious liver damage.
    Tips from our pharmacists for people taking the medication
    RelafenTylenol
    Coming soon
    • Tylenol Regular Strength (acetaminophen) starts working within one hour.
    • Taking too much of Tylenol Regular Strength (acetaminophen) can cause liver failure and death. Don't take more than what's recommended on the package insert.
    • Acetaminophen is found in many over-the-counter and prescription products. Make sure the total amount of acetaminophen you take does not exceed 3,000 mg per day and check with your pharmacist to make sure you're not taking too much.
    • Follow age-specific dosing instructions on how much to take.
    • Let your doctor know if your symptoms don't improve in a few days.
    Learn more
    More about RelafenSide effectsReviews & ratingsFDA package insert
    Have you used Relafen (nabumetone)?
    Worth itNot sureNot worth it
    More about TylenolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tylenol Regular Strength (acetaminophen)?
    Worth itNot sureNot worth it