Compare Relafen vs. Voltaren

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relafen (nabumetone)

Prescription only

Cambia (diclofenac)

Prescription only
Relieves pain and inflammation.

Relafen (nabumetone) works well for relieving pain and inflammation, but may take up to a week to kick in.

Relieves pain and inflammation.

Cambia (diclofenac) works well for pain and is available in many different forms. If you have a history of heart problems or stomach bleeds, it may not be the best choice.

4.2/ 5 average rating with 37 reviewsforVoltaren
Upsides
  • Relafen (nabumetone) is good for relieving pain and inflammation from osteoarthritis and rheumatoid arthritis.
  • Usually taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Relafen (nabumetone) causes less stomach upset and overall side effects than other NSAIDs, like ibuprofen and naproxen.
  • Works well to relieve muscle ache and pain caused by inflammation.
  • Minimal risk for addiction unlike narcotics.
  • Available in gel or powder packets if you have difficulty taking the pill.
  • Most forms are available as generic.
Downsides
  • Relafen (nabumetone) does not work as quickly as other NSAIDs.
  • Relafen (nabumetone), like other NSAIDS, is not safe for pregnant women and people who are age 60 or older.
  • Relafen (nabumetone) can cause serious complications including stomach bleeding and kidney problems if taken for a long period of time.
  • The safety and effectiveness of Relafen (nabumetone) for children are not known so they should not take it.
  • Not for chronic, daily use because of increased side-effects.
  • May need to be taken two or three-times daily for maximum pain relief.
  • Can cause serious stomach problems like inflammation, ulcers, and bleeding.
  • Can raise your risk of having blood clots, heart attack, or stroke.
  • Can lower kidney function or cause permanent kidney damage.
Used for
Dosage forms
  • Pill
  • Pill
  • Injection
Price
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Reviews
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37 reviews so far
81%
saidit'sworth it
76%
saiditworked well
5%
saidit'sa big hassle

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Side effects
3possible side effects
  • Diarrhea
    14%
  • Upset stomach
    13%
  • Stomach pain
    12%
See more detailed side effects
13possible side effects
  • Nausea
    24%
  • Constipation
    13%
  • Headache
    10%
  • Infusion site pain
    10%
  • Dizziness
    8%
  • Gas
    8%
  • Vomiting
    6%
  • Trouble sleeping
    6%
  • Itching
    5%
  • Low blood pressure
    5%
  • Fever
    4%
  • Low red blood counts
    4%
  • Infusion site leakage
    3%
See more detailed side effects
Risks and risk factors
  • Heart attack and stroke
    • History of heart problems
    • Taking Relafen (nabumetone) for a long period of time
  • Stomach bleeding
    • History of stomach bleeding and/or ulcers
    • Age 60 or older
    • Taking aspirin, other NSAIDs, steroids, or blood thinners
    • Drinking alcoholic beverages
    • Smoking
    • Taking the medicine for a long period of time
    • People with poor general health
  • Severe allergic reaction
    • Asthma
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Kidney damage
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking certain high blood pressure medications
    • Age 60 or older
    • Taking the medicine for a long period of time
  • Harm to fetus
    • Pregnant women
    • Women who want to or can become pregnant
  • Heart-related complications
    • Recent heart surgery or heart attack
    • History of high blood pressure
    • History of heart failure
See more detailed risks and warnings
  • Heart attack and stroke
    • History of heart problems
    • Taking Cambia (diclofenac) for a long period of time
  • Stomach bleeding
    • History of stomach bleeding
    • Age 60 or older
    • Taking aspirin, other NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
    • Smoking
    • Taking the medicine for a long period of time
  • Severe allergic reaction
    • Asthma
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Kidney damage
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking certain high blood pressure medications
    • Age 60 or older
    • Taking the medicine for a long period of time
  • Harm to fetus (unborn baby)
    • Women who want to or can become pregnant
    • Pregnant women
See more detailed risks and warnings