Compare Remicade vs. Rituxan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Remicade (infliximab)

Prescription only

Rituxan (Rituximab)

Prescription only
Calms down your immune system.

Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.

4.0/ 5 average rating with 55 reviewsforRemicade
Calms down your immune system.

Rituxan (Rituximab) is effective for treating multiple types of cancer and arthritis. That said, you'll need to watch for possibly serious side effects, especially infusion reactions.

Upsides
  • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
  • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
  • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
  • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
  • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • Treats leukemia, lymphoma, and blood vessel inflammation.
  • Also treats moderate to severe rheumatoid arthritis that hasn't responded to anti-TNF treatment (but you'll need to take methotrexate too).
  • The chance of having a reaction to the infusion is highest during your first dose, but the risk decreases each time you get Rituxan (Rituximab). It usually happens within 30 minutes to 2 hours after starting the infusion.
  • Rituxan (Rituximab) is a targeted therapy that works differently than chemotherapy. Both work well when they're taken together, especially when treating CLL and NHL.
Downsides
  • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
  • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
  • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
  • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
  • No generic available, so it can be costly.
  • Only your doctor or other trained medical staff can administer Rituxan (Rituximab), so you'll need to go into an office or clinic for every dose.
  • Not the best choice if you have heart problems.
  • Rituxan (Rituximab) can stay in your body for up to 6 months after you complete treatment. Men and women who are able to have children need to use birth control for up to one year after finishing Rituxan (Rituximab).
  • Discuss with your doctor the serious heart, kidney, liver, or stomach problems that can happen while on Rituxan (Rituximab).
Used for
Dosage forms
  • Injection
  • Infusion (IV)
Price
Lowest price
$20695.40
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Reviews
55 reviews so far
76%
saidit'sworth it
62%
saiditworked well
15%
saidit'sa big hassle

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Side effects
The Remicade (infliximab) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Any infection
    62%
  • Infusion reaction
    12%
  • Any serious infection
    11%
  • Cardiac side effect
    2%
See more detailed side effects
Risks and risk factors
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 65 or older
    • Comorbidities
  • Cancer
    • Taking other immunosuppressant drugs
    • History of malignancy
  • Heart failure
    • History of heart failure
    • Receiving higher doses
  • Nervous system effects
    • History of nerve problems
  • Lower blood cell counts
    • Ongoing or history of blood problems
  • Liver injury
See more detailed risks and warnings
  • Serious allergic reactions
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
  • Nervous system effects
    • Taking Rituxan (Rituximab) with immunosuppressant drugs (if using for RA)
    • Taking Rituxan (Rituximab) with chemotherapy (if using for NHL or CLL
    • Stem cell transplant
  • Skin and mouth reactions
  • Kidney injury
    • Taking Rituxan (Rituximab) for Non-Hodgkin's Lymphoma (NHL)
    • Rapidly growing tumors
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Gastrointestinal problems
    • Start of therapy with Rituxan (Rituximab)
  • Blood problems
See more detailed risks and warnings