Compare Remicade vs. Stelara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Remicade (infliximab)

Prescription only

Stelara (Ustekinumab)

Prescription only
Calms down your immune system.

Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.

4.0/ 5 average rating with 55 reviewsforRemicade
Treats moderate to severe psoriasis.

Stelara (Ustekinumab) works for two psoriatic conditions. It may be somewhat of a hassle because of the injection, but after the first two doses, you only need to take it every 12 weeks.

3.1/ 5 average rating with 50 reviewsforStelara
Upsides
  • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
  • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
  • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
  • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
  • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • Stelara (Ustekinumab) works throughout your whole body (systemic therapy) and may be better than just applying medicine to your skin (local therapy) for moderate or severe plaque psoriasis that covers large areas or many areas of your body.
  • It's used alone or together with another medicine called methotrexate for better results to treat active psoriatic arthritis.
  • Initial dosing might be a hassle, but then you only have to take it every 12 weeks.
  • People treated with Stelara (Ustekinumab) for psoriatic arthritis felt better and had more physical improvement compared to not using the medicine (placebo).
Downsides
  • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
  • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
  • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
  • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
  • No generic available, so it can be costly.
  • It's an injection.
  • Stelara (Ustekinumab) lowers your ability to fight infection and can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You have to get your first dose of Stelara (Ustekinumab) at your doctor's office. If you decide not to self-inject and don't have someone to do it for you, you'll need to continue to see your doctor for each dose.
  • You'll need to properly dispose of the needle and syringes in a special (FDA-approved) sharps container.
  • Because Stelara (Ustekinumab) needs to be refrigerated until you use it, if you're traveling, you'll need to carry it in a cooler with an ice pack.
Used for
Dosage forms
  • Injection
  • Injection
Price
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$20695.40
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$18783.00
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Reviews
55 reviews so far
76%
saidit'sworth it
62%
saiditworked well
15%
saidit'sa big hassle

Have you used Remicade (infliximab)?

Leave a review
50 reviews so far
48%
saidit'sworth it
42%
saiditworked well
20%
saidit'sa big hassle

Have you used Stelara (Ustekinumab)?

Leave a review
Side effects
The Remicade (infliximab) FDA package insert doesn’t have numbers about how common side effects are.
1possible side effects
  • Immunogenicity
    6%
See more detailed side effects
Risks and risk factors
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 65 or older
    • Comorbidities
  • Cancer
    • Taking other immunosuppressant drugs
    • History of malignancy
  • Heart failure
    • History of heart failure
    • Receiving higher doses
  • Nervous system effects
    • History of nerve problems
  • Lower blood cell counts
    • Ongoing or history of blood problems
  • Liver injury
See more detailed risks and warnings
  • Serious Infections
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
  • Possible infections
  • Serious allergic reactions
  • Malignancy
    • Age 60 or older
    • Long-term use of drugs that suppress the immune system
    • History of PUVA (photochemotherapy)
  • Nervous system effects
    • Preeclampsia/eclampsia
    • Acute hypertension
    • Taking other drugs that suppress the immune system
    • Taking cytotoxic chemotherapy
  • Drug interactions
  • Risk to fetus
See more detailed risks and warnings