Compare Restoril vs. Anafranil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Restoril
(Temazepam)

Anafranil
(Clomipramine)

Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.Helps with your actions. Anafranil (Clomipramine) is helpful in treating OCD, but it can have a lot of side effects.
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Reviews & ratings
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5.222222222222222Restoril
Reviews for Restoril (Temazepam)
56%
of people say Restoril (Temazepam) is worth it
56%
say it works well
22%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
RestorilAnafranil

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »
  • Dry mouth 67%
  • Tremor 52%
  • Dizziness 40%
  • Ejaculation failure 40%
  • Drowsiness 38%
  • Constipation 36%
  • Increased sweating 26%
  • Fatigue 21%
  • Loss of appetite 20%
  • Nausea 19%
More Anafranil side effects »
How it works
RestorilAnafranil
Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.Anafranil (Clomipramine) is a tricyclic antidepressant (TCA). It treats obsessive-compulsive disorder by affecting the levels of serotonin and norepinephrine in your brain.
Type of medication
RestorilAnafranil
Anti-anxiety
Benzodiazepine
Prescription only
Antidepressant
Tricyclic antidepressant (TCA)
Prescription only
Available as
RestorilAnafranil
  • Pill
  • Pill
Used for (click to learn more)
RestorilAnafranil
Risk factors for serious side effects
RestorilAnafranil
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Women of childbearing age
  • Alcohol
  • Taking other medicines that make you less alert
    • Taking with alcohol
    • Taking with other drugs that acts in the brain
    • Age 65 or older
    Detailed Restoril (Temazepam) risks & warnings »
    • Age 24 years or younger
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Using other medications that affect serotonin
    • History of seizure
    • Taking other medicines that increase seizure risk
    • Alcoholism
    • Stopping Anafranil (Clomipramine) suddenly
    • Age 65 years or older
    • History of heart disease
    • Older age
    • Electrolyte imbalance
    Detailed Anafranil (Clomipramine) risks & warnings »
    Pregnancy category
    RestorilAnafranil
    XFDA pregnancy category (Unsafe)

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    • It is not safe to drink alcohol while taking this.
    • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
    No specific alcohol-related info.
    Food
    No specific food-related info.
    • Take it with food and/or at bedtime to decrease the potential side effects.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.
    • Can cause sexual performance problems in men.
    Sleep
    • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • Use only as needed when you can't sleep.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Stopping Restoril (Temazepam) suddenly can cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and muscle pain or burning. Withdrawal symptoms can last 6 weeks or longer. Work with your doctor to gradually reduce your dose.
    • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
    • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
    • Can help you sleep.
    • Stopping Anafranil (Clomipramine) suddenly may cause withdrawal symptoms such as nausea, anxiety, agitation, flu-like symptoms, trouble sleeping, and dizziness. Withdrawal symptoms usually occur within 3-5 days of stopping the medication, and go away within 1-2 weeks. Work with your doctor to gradually reduce your dose.
    Weight
    No specific weight-related info.
    • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
    Upsides and benefits
    RestorilAnafranil
    • Helps you fall asleep and stay asleep.
    • Can be helpful to reduce anxiety.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • Works well to decrease the symptoms of obsessive-compulsive disorder (OCD).
    • Helps some people see improvements in their mood.
    • Can help you sleep.
    • Lower risk of causing heart problems compared to other medicine in this class.
    Downsides and risks
    RestorilAnafranil
    • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
    • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
    • It's not recommended for people age 65 years or older.
    • Can't be used by pregnant women since it'll cause harm to the baby.
    • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
    • It's more likely to cause side effects like dizziness, drowsiness, weight gain, and constipation compared to other medicines in this class.
    • Can cause sexual performance problems in men.
    • Increases the risk of falls, especially when used in the elderly.
    Tips from our pharmacists for people taking the medication
    RestorilAnafranil
    • Use only as needed when you can't sleep.
    • Starts working within 45 minutes.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Take it only if you can get a full night's rest.
    • It is not safe to drink alcohol while taking this.
    • Tell your doctor if you notice any changes to your memory or mood.
    • Needs to be taken every day for 2 to 3 weeks to see the full effect of the medication.
    • It's important to keep taking Anafranil (Clomipramine) even when you feel your symptoms are getting better.
    • Take it with food and/or at bedtime to decrease the potential side effects.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    • If you decide to stop taking Anafranil (Clomipramine), work with your doctor to slowly get off this medicine to avoid getting withdrawal symptoms.
    Learn more
    More about RestorilSide effectsReviews & ratingsAlternativesFDA package insert
    More about AnafranilSide effectsReviews & ratingsAlternativesFDA package insert