Compare Restoril vs. Doxepin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Restoril
(temazepam)

Zonalon
(doxepin)

Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.Helps you stop itching. Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.
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Coupons for Restoril
Best available price for 30 (15mg) capsules of temazepam
Coupons for Doxepin
Best available price for 30 (10mg) capsules of doxepin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.29Restoril
Reviews for Restoril
65%
of people (All ages) say Restoril is worth it
55%
say it works well
16%
say it's a big hassle
Have you used Restoril (temazepam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Zonalon (doxepin)?
Worth itNot sureNot worth it
Side effects
RestorilDoxepin

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »

We haven’t found good data for Doxepin side effects.

FDA side effect reports for Doxepin »
How it works
RestorilDoxepin
Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.Zonalon (Doxepin) is an cream that stops you from itching by blocking the chemical receptors that cause itching.
Type of medication
RestorilDoxepin
Prescription onlyPrescription only
Available as
RestorilDoxepin
  • Pill
  • Cream, gel, or ointment
Used for
RestorilDoxepin
  • Skin Intching Moderate
Risk factors for serious side effects
RestorilDoxepin
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Women of childbearing age
Detailed Restoril (temazepam) risks & warnings »
    Detailed Zonalon (doxepin) risks & warnings »
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Price
    RestorilDoxepin
    No price related info.
    • It isn't available as a generic, so it could be kind of pricey.
    Interactions
    RestorilDoxepin
    No interactions related info.
    • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
    Alcohol
    RestorilDoxepin
    • It is not safe to drink alcohol while taking this.
    No alcohol related info.
    Sleep
    RestorilDoxepin
    • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • Zonalon (Doxepin) can make you sleepy.
    Upsides and benefits
    RestorilDoxepin
    • Helps you fall asleep and stay asleep.
    • Can be helpful to reduce anxiety.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
    • You can use Zonalon (Doxepin) for up to 8 days at a time.
    Downsides and risks
    RestorilDoxepin
    • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
    • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
    • It's not recommended for people age 65 years or older.
    • Can't be used by pregnant women since it'll cause harm to the baby.
    • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
    • You need a prescription for Zonalon (Doxepin).
    • It isn't available as a generic, so it could be kind of pricey.
    • Zonalon (Doxepin) can make you sleepy.
    • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
    Tips from our pharmacists for people taking the medication
    RestorilDoxepin
    • Use only as needed when you can't sleep.
    • Starts working within 45 minutes.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Take it only if you can get a full night's rest.
    • It is not safe to drink alcohol while taking this.
    • Tell your doctor if you notice any changes to your memory or mood.
    • Be sure the affected area is clean and dry before applying Zonalon (Doxepin).
    • Wash your hands before and after using it.
    • Apply a thin layer of Zonalon (Doxepin) onto the affected area and rub it in gently.
    • Don’t put a bandage, dressing, or make-up over Zonalon (Doxepin) once it's on your skin.
    • It shouldn't affect you too much, but avoid activities that need you to be fully alert (like driving) until you know how it works.
    Learn more
    More about RestorilSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Restoril (temazepam)?
    Worth itNot sureNot worth it
    More about DoxepinSide effectsFDA package insert
    Have you used Zonalon (doxepin)?
    Worth itNot sureNot worth it