Compare Restoril vs. desipramine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Restoril (Temazepam)

Prescription only

Norpramin (desipramine)

Prescription only
Helps you relax and sleep.

Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.

5.3/ 7 average rating with 51 reviewsforRestoril
Stabilizes your mood.

Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.

Upsides
  • Helps you fall asleep and stay asleep.
  • Can be helpful to reduce anxiety.
  • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
  • Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
  • Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
Downsides
  • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
  • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
  • It's not recommended for people age 65 years or older.
  • Can't be used by pregnant women since it'll cause harm to the baby.
  • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
  • Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
  • Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
  • In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
  • If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
  • Not recommended in children under 12 years of age.
Used for
Dosage forms
  • Pill
  • Pill
Price
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$9.2
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$15.87
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Reviews
51 
65%
think this treatment is worth it
55%
think this treatment works well
16%
think this treatment is a hassle

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Side effects
The Restoril (Temazepam) FDA package insert doesn’t have numbers about how common side effects are.
The Norpramin (desipramine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Tolerance and dependence

    Taking more than the prescribed dose

    ...and 2 more risk factors

  • Withdrawal

    Long-term use

  • Harm to fetus

    Women of childbearing age

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

  • Falls

    Taking with alcohol

    ...and 2 more risk factors

See more detailed risks and warnings
  • Higher risk of suicide

    People under age 24

  • Serotonin syndrome

    Tricyclic antidepressants

    ...and 5 more risk factors

  • Changes to the heartbeat

    History of heart disease

  • Higher risk for seizures

    History of seizures

    ...and 1 more risk factors

See more detailed risks and warnings