Compare Restoril vs. desipramine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Restoril
(temazepam)

Norpramin
(desipramine)

Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.Stabilizes your mood. Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven't worked.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Restoril
Best available price for 30 (15mg) capsules of temazepam
Coupons for desipramine
Best available price for 30 (25mg) tablets of desipramine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.29Restoril
Reviews for Restoril
65%
of people (All ages) say Restoril is worth it
55%
say it works well
16%
say it's a big hassle
Have you used Restoril (temazepam)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Norpramin (desipramine)?
Worth itNot sureNot worth it
Side effects
Restorildesipramine

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »

The desipramine FDA package insert doesn’t have numbers about how common side effects are.

More about desipramine side effects »
How it works
Restorildesipramine
Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.Norpramin (desipramine) is a tricyclic antidepressant. It increases the amount of norepinephrine and serotonin in the brain, two chemicals that regulate mood.
Type of medication
Restorildesipramine
Prescription onlyPrescription only
Available as
Restorildesipramine
  • Pill
  • Pill
Used for
Restorildesipramine
Risk factors for serious side effects
Restorildesipramine
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Women of childbearing age
Detailed Restoril (temazepam) risks & warnings »
  • People under age 24
  • Tricyclic antidepressants
  • Fentanyl
  • Tramadol
  • Buspirone
Detailed Norpramin (desipramine) risks & warnings »
Pregnancy

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
Restorildesipramine
  • It is not safe to drink alcohol while taking this.
No alcohol related info.
Sleep
Restorildesipramine
  • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
  • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
  • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
No sleep related info.
Upsides and benefits
Restorildesipramine
  • Helps you fall asleep and stay asleep.
  • Can be helpful to reduce anxiety.
  • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
  • Norpramin (desipramine) is available in generic and in many different strengths, so the dose can be more customized.
  • Norpramin (desipramine) has fewer side effects than similar tricyclic antidepressants.
Downsides and risks
Restorildesipramine
  • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
  • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
  • It's not recommended for people age 65 years or older.
  • Can't be used by pregnant women since it'll cause harm to the baby.
  • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
  • Norpramin (desipramine) isn't recommended if you or your family has heart disease, seizures, or glaucoma.
  • Norpramin (desipramine) isn't a first choice for depression because it has more side effects than other antidepressants.
  • In some people, Norpramin (desipramine) can make you sleepy. In other people, Norpramin (desipramine) can keep you awake.
  • If you have diabetes, Norpramin (desipramine) can make your blood sugar go up.
  • Not recommended in children under 12 years of age.
Tips from our pharmacists for people taking the medication
Restorildesipramine
  • Use only as needed when you can't sleep.
  • Starts working within 45 minutes.
  • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
  • Take it only if you can get a full night's rest.
  • It is not safe to drink alcohol while taking this.
  • Tell your doctor if you notice any changes to your memory or mood.
  • Don't drive or do anything requiring concentration until you know how Norpramin (desipramine) affects you since it can make you feel sleepy.
  • Talk to your doctor right away if your mood suddenly darkens and you want to hurt yourself while taking Norpramin (desipramine).
  • If you're being switched to Norpramin (desipramine) from monoamine oxidase inhibitors, you'll need to wait 2 weeks before you can start it.
  • Don't stop taking Norpramin (desipramine) suddenly without talking to your doctor first.
Learn more
More about RestorilSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Restoril (temazepam)?
Worth itNot sureNot worth it
More about desipramineSide effectsAlternativesFDA package insert
Have you used Norpramin (desipramine)?
Worth itNot sureNot worth it