Compare Restoril vs. Silenor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Restoril
(temazepam)

Silenor
(doxepin)

Helps you relax and sleep. Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.Helps you relax, and sleep. Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.
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Coupons for Restoril
Best available price for 30 (15mg) capsules of temazepam
Coupons for Silenor
Best available price for 30 (10mg) capsules of doxepin
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.29Restoril
Reviews for Restoril
65%
of people (All ages) say Restoril is worth it
55%
say it works well
16%
say it's a big hassle
Have you used Restoril (temazepam)?
Worth itNot sureNot worth it

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Have you used Silenor (doxepin)?
Worth itNot sureNot worth it
Side effects
RestorilSilenor

We haven’t found good data for Restoril side effects.

FDA side effect reports for Restoril »

We haven’t found good data for Silenor side effects.

FDA side effect reports for Silenor »
How it works
RestorilSilenor
Restoril (Temazepam) is a benzodiazepine. It affects chemicals in the brain to calm down your nervous system, helping you sleep and be less anxious.Doxepin is a tricyclic antidepressant. It keeps norepinephrine and serotonin in your brain longer, helping you relax, and sleep. It also blocks the chemical that causes itch, and wakefulness.
Type of medication
RestorilSilenor
Prescription only
Available as
RestorilSilenor
  • Pill
  • Pill
  • Liquid
Used for
RestorilSilenor
  • Alcoholism Anxiety Depression Anxiety Depression Anxiety Depression Psychoneurotic Personality Disorder Insomnia Pruritus Moderate
Risk factors for serious side effects
RestorilSilenor
  • Taking more than the prescribed dose
  • Taking longer than 4 weeks
  • History of drug abuse
  • Long-term use
  • Women of childbearing age
Detailed Restoril (temazepam) risks & warnings »
    Coming soon.
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    RestorilSilenor
    No interactions related info.
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    Alcohol
    RestorilSilenor
    • It is not safe to drink alcohol while taking this.
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    Sleep
    RestorilSilenor
    • Restoril (Temazepam) can make you dizzy and drowsy, especially when combined with alcohol and many other medicines that acts in your brain. It is not recommended for people age 65 years or older.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    No sleep related info.
    Weight
    RestorilSilenor
    No weight related info.
    • Doxepin can increase your appetite, leading to weight gain.
    Upsides and benefits
    RestorilSilenor
    • Helps you fall asleep and stay asleep.
    • Can be helpful to reduce anxiety.
    • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
    • In a clinical trial Doxepin was able to significantly improve sleep quality.
    • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
    • Once your body gets used to Doxepin, most of the side effects go away.
    • Doxepin comes in a generic form, so it is pretty cheap.
    • Doxepin is not addictive.
    Downsides and risks
    RestorilSilenor
    • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
    • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
    • It's not recommended for people age 65 years or older.
    • Can't be used by pregnant women since it'll cause harm to the baby.
    • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
    • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
    • Doxepin can increase your appetite, leading to weight gain.
    • Taking Doxepin can make emptying your bladder difficult.
    • Some people have suicidal thoughts when taking Doxepin.
    • Doxepin can interact with many different medications, vitamins, and alternative treatments.
    Tips from our pharmacists for people taking the medication
    RestorilSilenor
    • Use only as needed when you can't sleep.
    • Starts working within 45 minutes.
    • Can cause dizziness and drowsiness, so don't do anything (like driving) after taking it that requires you to focus.
    • Take it only if you can get a full night's rest.
    • It is not safe to drink alcohol while taking this.
    • Tell your doctor if you notice any changes to your memory or mood.
    • Take Doxepin 30 minutes before bedtime so it starts working when you get in bed.
    • Avoid activities that need you to be fully alert like driving, until you know how Doxepin affects you.
    • Follow up with your doctor so he or she can make sure Doxepin is the right medication for your depression.
    • Stay away from alcohol while taking Doxepin, because it can slow your brain, and stop your breathing.
    • Some people get dry mouth, or constipation when taking Doxepin. Sugar free gum or candy can help the dry mouth, and drinking more fluid can help with constipation.
    • Avoid direct sunlight while taking this medication. When you can’t avoid it, be sure to use sunscreen. It’s also important to put on a long-sleeved shirt, pants, hat, and sunglasses.
    Learn more
    More about RestorilSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Restoril (temazepam)?
    Worth itNot sureNot worth it
    More about SilenorSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Silenor (doxepin)?
    Worth itNot sureNot worth it