Compare Risperdal vs. Saphris

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Risperdal
(Risperidone)

Saphris
(Asenapine)

Helps control your thoughts and mood. Risperdal (Risperidone) is good for treating psychosis, mania, and irritability. Among newer antipsychotic medicines, more likely to cause side effects, especially weight gain and hormone problems.Coming soon.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.448275862068965Risperdal
Reviews for Risperdal (Risperidone)
48%
of people say Risperdal (Risperidone) is worth it
41%
say it works well
48%
say it's a big hassle

Not enough reviews for this drug. Help someone out, leave a review!

Side effects
RisperdalSaphris
  • Relaxation or sleepiness 48%
  • Increased appetite 29%
  • Fatigue 22%
  • Parkinsonism 17%
  • Constipation 11%
  • Dizziness 11%
  • Abdominal pain upper 11%
  • Common cold 10%
  • Nausea 9%
  • Indigestion 8%
More Risperdal side effects »

We haven’t found good data for Saphris side effects.

FDA side effect reports for Saphris »
How it works
RisperdalSaphris
Risperdal (Risperidone) is an atypical antipsychotic. Researchers don't know exactly how it works. It seems to change dopamine and serotonin activity in your brain, which affects thoughts and mood.Coming soon.
Type of medication
RisperdalSaphris
Antipsychotic
Atypical
Prescription only
Coming soon.
Available as
RisperdalSaphris
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
  • Pill
Used for (click to learn more)
RisperdalSaphris
  • Bipolar I disorder
Risk factors for serious side effects
RisperdalSaphris
  • Elderly patients with dementia
      • History of heart problems
      • Drug interactions
        • People with diabetes
        • People with high cholesterol
        • People with diabetes
        • Alcohol
        • Taking other medicines that make you less alert
          Detailed Risperdal (Risperidone) risks & warnings »
          Coming soon.
          Pregnancy category
          RisperdalSaphris
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          • Risperdal (Risperidone) can increase your blood sugar and cholesterol. Exercise and eat healthy food to lower your risk.
          • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
          No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          • Can cause dizziness and drowsiness.
          No specific sleep-related info.
          Weight
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Risperdal (Risperidone) can cause you to gain weight. Exercise and eat healthy food to lower your risk.
          No specific weight-related info.
          Upsides and benefits
          RisperdalSaphris
          • Effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior.
          • Lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
          • Antipsychotic medicines are all about equally effective.
          • Less likely to cause heart problems than some antipsychotics.
          Coming soon.
          Downsides and risks
          RisperdalSaphris
          • Mild to moderate risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
          • Moderate risk of weight gain and problems with cholesterol or blood sugar compared to other antipsychotics.
          • Compared to other antipsychotics, higher risk of hormone problems that cause nipples to leak and male breasts to grow abnormally large.
          • You might need routine blood tests to check how the medicine is affecting your body.
          • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find one that works for you and that you can tolerate.
          Coming soon.
          Tips from our pharmacists for people taking the medication
          RisperdalSaphris
          • Takes 4 to 6 weeks to see full effects on thoughts and mood.
          • Can cause dizziness and drowsiness.
          • For the first week, avoid activities that require you to be alert.
          • May cause weight gain and worsen cholesterol or blood sugar.
          • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
          • Elderly people with dementia shouldn't take it.
          Coming soon.
          Learn more
          More about RisperdalSide effectsReviews & ratingsAlternativesFDA package insert
          More about SaphrisSide effectsReviews & ratingsFDA package insert