Compare Robaxin vs. baclofen

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robaxin
(methocarbamol)

Lioresal
(baclofen)

Coming soon.Relaxes your muscles. Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Robaxin (methocarbamol)?
Worth itNot sureNot worth it
Reviews for baclofen
61%
+6% better vs. Robaxin
55%
-44% worse vs. Robaxin
15%
+15% better vs. Robaxin
Have you used Lioresal (baclofen)?
Worth itNot sureNot worth it
Side effects
Robaxinbaclofen

We haven’t found good data for Robaxin side effects.

FDA side effect reports for Robaxin »
  • Drowsiness 27%
More baclofen side effects »
How it works
Robaxinbaclofen
Coming soon.Lioresal (baclofen) is a gamma-aminobutryic acid (GABA) agonist. It's not clear how it works, but GABA is believed to help calm down nerves. Muscle spasms are thought to be started by overactive nerves.
Type of medication
Robaxinbaclofen
Prescription only
Available as
Robaxinbaclofen
  • Pill
  • Pill
Used for
Robaxinbaclofen
  • Musculoskeletal Pain Spasm Tetanus
Risk factors for serious side effects
Robaxinbaclofen
    Coming soon.
    • Stopping Lioresal (baclofen) too quickly
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Age 65 or greater
    • Higher dose
    Detailed Lioresal (baclofen) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    Robaxinbaclofen
    No alcohol related info.
    • Avoid drinking alcohol while on Lioresal (baclofen) because it can make you very sleepy or slow your breathing down.
    Sleep
    Robaxinbaclofen
    No sleep related info.
    • Lioresal (baclofen) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    Upsides and benefits
    Robaxinbaclofen
    Coming soon
    • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
    • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
    Downsides and risks
    Robaxinbaclofen
    Coming soon
    • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
    • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
    • Lioresal (baclofen) can make you sleepy.
    • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
    Tips from our pharmacists for people taking the medication
    Robaxinbaclofen
    Coming soon
    • Lioresal (baclofen) can make you feel very tired or sleepy. Don't drive or do anything that requires concentration until you know how it affects you.
    • Don't stop taking Lioresal (baclofen) suddenly without talking to your doctor if you've been on it for a long time. It can be dangerous. Your doctor will help you get off it slowly over time.
    • Avoid drinking alcohol while on Lioresal (baclofen) because it can make you very sleepy or slow your breathing down.
    Learn more
    More about RobaxinSide effectsReviews & ratingsFDA package insert
    Have you used Robaxin (methocarbamol)?
    Worth itNot sureNot worth it
    More about baclofenSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Lioresal (baclofen)?
    Worth itNot sureNot worth it