Compare Robitussin DM vs. Delsym

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robitussin Dm
(guaifenesin / dextromethorphan)

Delsym
(dextromethorphan)

Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.05Robitussin DM
Reviews for Robitussin DM
75%
of people (All ages) say Robitussin DM is worth it
37%
say it works well
7%
say it's a big hassle
724 reviews
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
Reviews for Delsym
63%
+12% better vs. Robitussin DM
32%
+5% better vs. Robitussin DM
12%
+5% better vs. Robitussin DM
127 reviews
Have you used Delsym (dextromethorphan)?
Worth itNot sureNot worth it
Side effects
Robitussin DMDelsym

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »
How it works
Robitussin DMDelsym
Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Delsym (Dextromethorphan) is a cough suppressant.
Type of medication
Robitussin DMDelsym
Over-the-counterOver-the-counter
Available as
Robitussin DMDelsym
  • Liquid
  • Pill
  • Liquid extended release
Used for
Robitussin DMDelsym
Risk factors for serious side effects
Robitussin DMDelsym
  • Using other medications that affect serotonin
Detailed Robitussin Dm (guaifenesin / dextromethorphan) risks & warnings »
  • Using other medications that affect serotonin
Detailed Delsym (dextromethorphan) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Upsides and benefits
Robitussin DMDelsym
  • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
Downsides and risks
Robitussin DMDelsym
  • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
  • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
  • Can cause sleepiness, dizziness, and an upset stomach.
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
Tips from our pharmacists for people taking the medication
Robitussin DMDelsym
  • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
Learn more
More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Delsym (dextromethorphan)?
Worth itNot sureNot worth it