Compare Robitussin DM vs. Mucinex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robitussin Dm
(guaifenesin / dextromethorphan)

Mucinex
(guaifenesin)

Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.Breaks up mucus that causes cough. Mucinex (Guaifenesin) is a useful medicine for loosening congestion in your chest and throat, and it lasts longer than other guaifenesin products.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.05Robitussin DM
Reviews for Robitussin DM
75%
of people (All ages) say Robitussin DM is worth it
37%
say it works well
7%
say it's a big hassle
724 reviews
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
Reviews for Mucinex
78%
-3% worse vs. Robitussin DM
47%
-10% worse vs. Robitussin DM
7%
Same vs. Robitussin DM
902 reviews
Have you used Mucinex (guaifenesin)?
Worth itNot sureNot worth it
Side effects
Robitussin DMMucinex

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »

We haven’t found good data for Mucinex side effects.

FDA side effect reports for Mucinex »
How it works
Robitussin DMMucinex
Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Mucinex (Guaifenesin) is an expectorant. It contains guaifenesin, which thins and loosens mucus, making it easier to cough out.
Type of medication
Robitussin DMMucinex
Over-the-counterOver-the-counter
Available as
Robitussin DMMucinex
  • Liquid
  • Extended release
  • Liquid
Used for
Robitussin DMMucinex
Risk factors for serious side effects
Robitussin DMMucinex
  • Using other medications that affect serotonin
Detailed Robitussin Dm (guaifenesin / dextromethorphan) risks & warnings »
    Detailed Mucinex (guaifenesin) risks & warnings »
    Pregnancy

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Alcohol
    Robitussin DMMucinex
    No alcohol related info.
    • Mucinex (Guaifenesin) is alcohol- and sugar-free.
    Upsides and benefits
    Robitussin DMMucinex
    • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
    • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
    • Mucinex (Guaifenesin) reduces the thickness and amount of mucus in your throat and chest.
    • Lasts longer than some other products that contain guaifenesin, such as Robitussin, because it's an extended-release form.
    • It’s available at the drugstore either by itself or in combination with other medications to treat cold and flu symptoms.
    • Available in liquid and tablet forms.
    • Mucinex (Guaifenesin) is alcohol- and sugar-free.
    Downsides and risks
    Robitussin DMMucinex
    • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
    • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
    • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
    • Can cause sleepiness, dizziness, and an upset stomach.
    • Mucinex (Guaifenesin) is more expensive than other medications that treat congestion.
    • You need to drink a lot of fluids while taking this medication or it won't work as well.
    • Mucinex (Guaifenesin) isn’t useful if you have a dry cough.
    • Can cause nausea, headache, and an upset stomach.
    Tips from our pharmacists for people taking the medication
    Robitussin DMMucinex
    • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
    • Cough suppressant starts working in 15 to 30 minutes.
    • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
    • If your cough lasts more than 7 days, call your doctor.
    • Drink plenty of fluids while taking Mucinex (Guaifenesin) because liquid helps break down mucus.
    • Steam from a humidifier, cool mist vaporizer, or hot shower can also help add moisture to your airways.
    • Follow age-specific dosing instructions on how much to take.
    • If your cough lasts more than 7 days, call your doctor.
    • Mucinex (Guaifenesin) only works for coughs with mucus, so don't use it if you have a dry cough.
    Learn more
    More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
    Worth itNot sureNot worth it
    More about MucinexSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Mucinex (guaifenesin)?
    Worth itNot sureNot worth it