Compare Robitussin DM vs. Mucinex D

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robitussin Dm
(guaifenesin / dextromethorphan)

Mucinex D
(guaifenesin / pseudoephedrine)

Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.Breaks up mucus and relieves congestion. Mucinex D (Guaifenesin / Pseudoephedrine) is good if you have a stuffy nose and a cough with mucus, but it could keep you up at night.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.05Robitussin DM
Reviews for Robitussin Dm (guaifenesin / dextromethorphan)
75%
of people (All ages) say Robitussin Dm (guaifenesin / dextromethorphan) is worth it
37%
say it works well
7%
say it's a big hassle
724 reviews
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
Reviews for Mucinex D (guaifenesin / pseudoephedrine)
76%
+1% better vs. Robitussin Dm (guaifenesin / dextromethorphan)
41%
+4% better vs. Robitussin Dm (guaifenesin / dextromethorphan)
7%
Same vs. Robitussin Dm (guaifenesin / dextromethorphan)
1249 reviews
Have you used Mucinex D (guaifenesin / pseudoephedrine)?
Worth itNot sureNot worth it
Side effects
Robitussin DMMucinex D

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »

We haven’t found good data for Mucinex D side effects.

FDA side effect reports for Mucinex D »
How it works
Robitussin DMMucinex D
Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine. Guaifenesin (an expectorant) breaks up and thins out mucus. Pseudoephedrine (a decongestant) clears your sinuses.
Type of medication
Robitussin DMMucinex D
Over-the-counter
Over-the-counter
Available as
Robitussin DMMucinex D
  • Liquid
  • Extended release
Used for
Robitussin DMMucinex D
Risk factors for serious side effects
Robitussin DMMucinex D
  • Using other medications that affect serotonin
Detailed Robitussin Dm (guaifenesin / dextromethorphan) risks & warnings »
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
Detailed Mucinex D (guaifenesin / pseudoephedrine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Upsides and benefits
Robitussin DMMucinex D
  • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
  • Mucinex D (Guaifenesin / Pseudoephedrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have sinus and chest congestion.
  • Helps loosen the mucus in your airways so that you can cough it up more easily.
  • Works well to clear nasal congestion and help you breathe better.
Downsides and risks
Robitussin DMMucinex D
  • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
  • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
  • Can cause sleepiness, dizziness, and an upset stomach.
  • Pseudoephedrine, the decongestant in Mucinex D (Guaifenesin / Pseudoephedrine), can make your heart race or make you feel anxious and restless.
  • Doesn't work as well if you use it for more than 4 days at a time.
  • Although you don't need a prescription to get Mucinex D (Guaifenesin / Pseudoephedrine), you need to show a photo ID to buy it in the drugstore.
  • Mucinex D (Guaifenesin / Pseudoephedrine) isn’t useful if you have a dry cough.
Tips from our pharmacists for people taking the medication
Robitussin DMMucinex D
  • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
  • Drink plenty of fluids while taking Mucinex D (Guaifenesin / Pseudoephedrine) because liquid helps break down mucus.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • You need to show an ID to buy Mucinex D (Guaifenesin / Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Don't take Mucinex D (Guaifenesin / Pseudoephedrine) too close to bedtime since it can keep you awake.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
Learn more
More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
More about Mucinex DSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Mucinex D (guaifenesin / pseudoephedrine)?
Worth itNot sureNot worth it