Compare Robitussin Multi-Symptom Cold CF vs. Delsym

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robitussin Multi-Symptom Cold Cf
(dextromethorphan / guaifenesin / phenylephrine)

Delsym
(dextromethorphan)

Relieves cold symptoms. Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is okay for loosening congestion in your throat and sinuses, but it could prevent you from coughing the mucus up.Relieves coughing. Delsym (Dextromethorphan) is a good option for treating dry cough. It's not safe to take with MAO inhibitors though.
Reviews & ratings
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Have you used Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)?
Worth itNot sureNot worth it
Reviews for Delsym
63%
+37% better vs. Robitussin Multi-Symptom Cold CF
32%
+68% better vs. Robitussin Multi-Symptom Cold CF
12%
+12% better vs. Robitussin Multi-Symptom Cold CF
127 reviews
Have you used Delsym (dextromethorphan)?
Worth itNot sureNot worth it
Side effects
Robitussin Multi-Symptom Cold CFDelsym

We haven’t found good data for Robitussin Multi-Symptom Cold CF side effects.

FDA side effect reports for Robitussin Multi-Symptom Cold CF »

We haven’t found good data for Delsym side effects.

FDA side effect reports for Delsym »
How it works
Robitussin Multi-Symptom Cold CFDelsym
Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that treats cold symptoms. Guaifenesin breaks up mucus and phlegm. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.Delsym (Dextromethorphan) is a cough suppressant.
Type of medication
Robitussin Multi-Symptom Cold CFDelsym
Over-the-counterOver-the-counter
Available as
Robitussin Multi-Symptom Cold CFDelsym
  • Liquid
  • Pill
  • Liquid extended release
Used for
Robitussin Multi-Symptom Cold CFDelsym
Risk factors for serious side effects
Robitussin Multi-Symptom Cold CFDelsym
  • Using other medications that affect serotonin
  • History of high blood pressure
  • Taking MAO inhibitors
  • Women of childbearing age
Detailed Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine) risks & warnings »
  • Using other medications that affect serotonin
Detailed Delsym (dextromethorphan) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Upsides and benefits
Robitussin Multi-Symptom Cold CFDelsym
  • Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, congestion, and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • Good for treating dry cough.
  • Available in drugstores either by itself or in combination with other medications to treat cold and allergy symptoms.
  • Available as a liquid and a tablet.
  • Some products relieve cough for up to 12 hours.
Downsides and risks
Robitussin Multi-Symptom Cold CFDelsym
  • Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) isn’t useful if you have a dry cough without mucus or phlegm.
  • Two of the medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan stops you from coughing.
  • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • Can't take dextromethorphan if you're taking MAO inhibitors (drugs used to treat Parkinson's disease, depression, and other emotional conditions). If taken together, they will cause dangerously high blood pressure levels.
  • If you're taking this in combination with other cold and allergy medications, you should read labels closely to make sure you're not accidentally taking too much of a single ingredient.
Tips from our pharmacists for people taking the medication
Robitussin Multi-Symptom Cold CFDelsym
  • Cough suppressant starts working in 15 to 30 minutes.
  • Drink plenty of fluids while taking Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) because liquid helps break down mucus.
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
  • Cough suppressant starts working in 15 to 30 minutes.
  • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
  • If your cough lasts more than 7 days, call your doctor.
Learn more
More about Robitussin Multi-Symptom Cold CFSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)?
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More about DelsymSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Delsym (dextromethorphan)?
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