Compare Robitussin Multi-Symptom Cold CF vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Robitussin Multi-Symptom Cold Cf
(dextromethorphan / guaifenesin / phenylephrine)

Robitussin Dm
(guaifenesin / dextromethorphan)

Relieves cold symptoms. Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is okay for loosening congestion in your throat and sinuses, but it could prevent you from coughing the mucus up.Breaks up mucus and relieves cough. Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.
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Reviews & ratings
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Have you used Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)?
Worth itNot sureNot worth it
Reviews for Robitussin Dm (guaifenesin / dextromethorphan)
75%
-25% worse vs. Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)
37%
-63% worse vs. Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)
7%
-7% worse vs. Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)
724 reviews
Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
Worth itNot sureNot worth it
Side effects
Robitussin Multi-Symptom Cold CFRobitussin DM

We haven’t found good data for Robitussin Multi-Symptom Cold CF side effects.

FDA side effect reports for Robitussin Multi-Symptom Cold CF »

We haven’t found good data for Robitussin DM side effects.

FDA side effect reports for Robitussin DM »
How it works
Robitussin Multi-Symptom Cold CFRobitussin DM
Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that treats cold symptoms. Guaifenesin breaks up mucus and phlegm. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine. Guaifenesin is an expectorant that breaks up and thins out mucus. Dextromethorphan is a cough suppressant.
Type of medication
Robitussin Multi-Symptom Cold CFRobitussin DM
Over-the-counter
Over-the-counter
Available as
Robitussin Multi-Symptom Cold CFRobitussin DM
  • Liquid
  • Liquid
Used for
Robitussin Multi-Symptom Cold CFRobitussin DM
Risk factors for serious side effects
Robitussin Multi-Symptom Cold CFRobitussin DM
  • Using other medications that affect serotonin
  • History of high blood pressure
  • Taking MAO inhibitors
    • Women of childbearing age
    Detailed Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine) risks & warnings »
      • Using other medications that affect serotonin
        Detailed Robitussin Dm (guaifenesin / dextromethorphan) risks & warnings »
        Pregnancy

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        Upsides and benefits
        Robitussin Multi-Symptom Cold CFRobitussin DM
        • Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, congestion, and a cough.
        • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
        • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
        • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
        • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
        Downsides and risks
        Robitussin Multi-Symptom Cold CFRobitussin DM
        • Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) isn’t useful if you have a dry cough without mucus or phlegm.
        • Two of the medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan stops you from coughing.
        • Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
        • You shouldn't use it if you have high blood pressure.
        • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
        • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
        • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
        • Can cause sleepiness, dizziness, and an upset stomach.
        Tips from our pharmacists for people taking the medication
        Robitussin Multi-Symptom Cold CFRobitussin DM
        • Cough suppressant starts working in 15 to 30 minutes.
        • Drink plenty of fluids while taking Robitussin Multi-Symptom Cold Cf (Dextromethorphan / Guaifenesin / Phenylephrine) because liquid helps break down mucus.
        • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
        • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
        • Let your doctor know if your symptoms don't improve in a few days, or if you have a really bad sore throat with a fever, headache, nausea, or vomiting.
        • Drink plenty of fluids while taking Robitussin Dm (Guaifenesin / Dextromethorphan) because liquid helps break down mucus.
        • Cough suppressant starts working in 15 to 30 minutes.
        • Follow age-specific dosing instructions on how much to take. Don't take more than the recommended dose.
        • If your cough lasts more than 7 days, call your doctor.
        Learn more
        More about Robitussin Multi-Symptom Cold CFSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Robitussin Multi-Symptom Cold Cf (dextromethorphan / guaifenesin / phenylephrine)?
        Worth itNot sureNot worth it
        More about Robitussin DMSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Robitussin Dm (guaifenesin / dextromethorphan)?
        Worth itNot sureNot worth it