Compare Rozerem vs. Ativan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Rozerem
(ramelteon)

Ativan
(lorazepam)

Helps you fall asleep. Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.Helps you relax. Ativan (lorazepam) is an effective medicine for occasional or short-term anxiety. It's less likely to have drug interactions, but more likely to cause withdrawal symptoms compared to similar drugs.
Reviews & ratings
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Have you used Rozerem (ramelteon)?
Worth itNot sureNot worth it
Reviews for Ativan
71%
-71% worse vs. Rozerem
51%
-51% worse vs. Rozerem
15%
+15% better vs. Rozerem
642 reviews
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it
Side effects
RozeremAtivan
  • Dizziness 1%
  • Sleepiness 1%
  • Fatigue 1%
  • Nausea 1%
  • Worsening insomnia 1%
More Rozerem side effects »
  • Sleepiness 16%
  • Dizziness 7%
  • Weakness 4%
  • Unsteadiness 3%
More Ativan side effects »
How it works
RozeremAtivan
Rozerem (ramelteon) is a melatonin receptor agonist. Melatonin is a chemical the body uses to maintain a normal sleeping cycle; Rozerem (ramelteon) helps you fall asleep and stay asleep.Ativan (lorazepam) is a fast-acting benzodiazepine. It affects areas of the brain that help calm you down. This reduces anxiety and can cause sleepiness.
Type of medication
RozeremAtivan
Prescription onlyPrescription only
Available as
RozeremAtivan
  • Pill
  • Pill
  • Liquid
  • Injection
Used for
RozeremAtivan
Risk factors for serious side effects
RozeremAtivan
  • Alcohol
  • Taking narcotics, tranquilizers, or antihistamines
Detailed Rozerem (ramelteon) risks & warnings »
  • Taking with opioids
  • Taking more than the prescribed dose
  • Taking Ativan (lorazepam) for longer than 4 weeks
  • History of drug abuse
  • Long-term use
Detailed Ativan (lorazepam) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Interactions
RozeremAtivan
No interactions related info.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Alcohol
RozeremAtivan
  • While taking Rozerem (ramelteon), don't drink alcohol or take other medicines that can make you sleepy, like opioids for pain relief, or benzodiazepines for anxiety.
  • Not safe to use with alcohol.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
Pain
RozeremAtivan
  • If you’re taking Rozerem (ramelteon), you need to be very careful about drinking alcohol, or taking medicines such as narcotics for pain relief, tranquilizers for anxiety, or antihistamines. Taking Rozerem (ramelteon) with alcohol or these medicines can slow down your central nervous system to the point where you stop breathing. Talk to your doctor to see if you should change your other medicines while you take Rozerem (ramelteon).
No pain related info.
Sleep
RozeremAtivan
  • Don't take Rozerem (ramelteon) if you're not able to sleep for at least 8 hours.
  • If you're not sleeping better after taking Rozerem (ramelteon) for 7 to 10 days, talk to your doctor.
  • Can cause temporary dizziness and drowsiness.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
Upsides and benefits
RozeremAtivan
  • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
  • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
  • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
  • Effective at relieving short-term anxiety.
  • Can be used together with antidepressants to manage anxiety disorders. Especially helpful for anxiety symptoms while you wait for an antidepressant to kick in.
  • Less likely to have drug interactions compared to other drugs like it, so it might be a better option if you're taking multiple medications.
Downsides and risks
RozeremAtivan
  • Rozerem (ramelteon) is only available as a brand name.
  • Rozerem (ramelteon) is only available in 1 strength.
  • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
  • Not recommended for children.
  • Rozerem (ramelteon) can't be used if you have sleep apnea.
  • Can cause memory problems, drowsiness, dizziness, and confusion.
  • Can be habit-forming, so it's not typically used for long-term treatment or for people who've had problems with drug or alcohol abuse.
  • Compared to other similar medicines, Ativan (lorazepam) is more likely to cause withdrawal if you take it for a long time and then suddenly stop.
  • Most people find that Ativan (lorazepam) gets less effective over time.
Tips from our pharmacists for people taking the medication
RozeremAtivan
  • Take Rozerem (ramelteon) on an empty stomach 30 minutes before you sleep.
  • Don't take Rozerem (ramelteon) if you're not able to sleep for at least 8 hours.
  • Swallow the Rozerem (ramelteon) tablet whole; don't break or crush it.
  • While taking Rozerem (ramelteon), don't drink alcohol or take other medicines that can make you sleepy, like opioids for pain relief, or benzodiazepines for anxiety.
  • If you're not sleeping better after taking Rozerem (ramelteon) for 7 to 10 days, talk to your doctor.
  • Can cause temporary dizziness and drowsiness.
  • Take only as much as your doctor prescribes. Taking more than directed or taking this for a long time can cause you to become dependent on it.
  • Not safe to use with alcohol.
  • Use caution or avoid use in older adults.
Learn more
More about RozeremSide effectsAlternativesFDA package insert
Have you used Rozerem (ramelteon)?
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More about AtivanSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Ativan (lorazepam)?
Worth itNot sureNot worth it