Compare Rozerem vs. Hetlioz

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Rozerem
(ramelteon)

Hetlioz
(tasimelteon)

Helps you fall asleep. Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.Keeps the sleep cycle normal for completely blind people who aren't able to see light. Hetlioz (tasimelteon) is the only approved medicine to help completely blind people who are unable to see light maintain regular sleep cycles. It is only available as a brand name, so it can be expensive.
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Coupons for Rozerem
Best available price for 30 (8mg) tablets of rozerem
Coupons for Hetlioz
Best available price for 30 (20mg) capsules of hetlioz
Reviews & ratings
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Have you used Rozerem (ramelteon)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Hetlioz (tasimelteon)?
Worth itNot sureNot worth it
Side effects
RozeremHetlioz
  • Dizziness 1%
  • Sleepiness 1%
  • Fatigue 1%
  • Nausea 1%
  • Worsening insomnia 1%
More Rozerem side effects »
  • Headache 10%
  • Abnormal liver tests 5%
  • Nightmares or abnormal dreams 10%
  • Common cold or flu 7%
  • Urinary tract infection 5%
More Hetlioz side effects »
How it works
RozeremHetlioz
Rozerem (ramelteon) is a melatonin receptor agonist. Melatonin is a chemical the body uses to maintain a normal sleeping cycle; Rozerem (ramelteon) helps you fall asleep and stay asleep.Hetlioz (tasimelteon) is a melatonin receptor agonist. It helps you to sleep at night and stay awake during the day.
Type of medication
RozeremHetlioz
Prescription onlyPrescription only
Available as
RozeremHetlioz
  • Pill
  • Pill
Used for
RozeremHetlioz
  • Non 24 Hour Sleep Wake Cycle
Risk factors for serious side effects
RozeremHetlioz
  • Alcohol
  • Taking narcotics, tranquilizers, or antihistamines
Detailed Rozerem (ramelteon) risks & warnings »
    Detailed Hetlioz (tasimelteon) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    RozeremHetlioz
    • While taking Rozerem (ramelteon), don't drink alcohol or take other medicines that can make you sleepy, like opioids for pain relief, or benzodiazepines for anxiety.
    No alcohol related info.
    Pain
    RozeremHetlioz
    • If you’re taking Rozerem (ramelteon), you need to be very careful about drinking alcohol, or taking medicines such as narcotics for pain relief, tranquilizers for anxiety, or antihistamines. Taking Rozerem (ramelteon) with alcohol or these medicines can slow down your central nervous system to the point where you stop breathing. Talk to your doctor to see if you should change your other medicines while you take Rozerem (ramelteon).
    No pain related info.
    Sleep
    RozeremHetlioz
    • Don't take Rozerem (ramelteon) if you're not able to sleep for at least 8 hours.
    • If you're not sleeping better after taking Rozerem (ramelteon) for 7 to 10 days, talk to your doctor.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    Upsides and benefits
    RozeremHetlioz
    • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
    • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
    • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
    • Hetlioz (tasimelteon) is not addictive.
    • Hetlioz (tasimelteon) is the only drug that's approved to help people unable to see light to have regular sleep cycles.
    • If you have to stop taking Hetlioz (tasimelteon) suddenly, you're not likely to have withdrawal.
    Downsides and risks
    RozeremHetlioz
    • Rozerem (ramelteon) is only available as a brand name.
    • Rozerem (ramelteon) is only available in 1 strength.
    • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
    • Not recommended for children.
    • Rozerem (ramelteon) can't be used if you have sleep apnea.
    • Hetlioz (tasimelteon) can take weeks to months for you to notice any effect.
    • Hetlioz (tasimelteon) is only available as a brand name so it can be expensive.
    Tips from our pharmacists for people taking the medication
    RozeremHetlioz
    • Take Rozerem (ramelteon) on an empty stomach 30 minutes before you sleep.
    • Don't take Rozerem (ramelteon) if you're not able to sleep for at least 8 hours.
    • Swallow the Rozerem (ramelteon) tablet whole; don't break or crush it.
    • While taking Rozerem (ramelteon), don't drink alcohol or take other medicines that can make you sleepy, like opioids for pain relief, or benzodiazepines for anxiety.
    • If you're not sleeping better after taking Rozerem (ramelteon) for 7 to 10 days, talk to your doctor.
    • Take Hetlioz (tasimelteon) at the same time every night.
    • Take Hetlioz (tasimelteon) on an empty stomach. Swallow capsule whole. Don't crush or chew the capsule.
    • If you go to sleep at a different time, don't take Hetlioz (tasimelteon).
    • Hetlioz (tasimelteon) might take weeks or months before you notice any effects.
    • If you smoke tobacco, Hetlioz (tasimelteon) might not work as well.
    Learn more
    More about RozeremSide effectsAlternativesFDA package insert
    Have you used Rozerem (ramelteon)?
    Worth itNot sureNot worth it
    More about HetliozSide effectsFDA package insert
    Have you used Hetlioz (tasimelteon)?
    Worth itNot sureNot worth it