Compare Rozerem vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Rozerem (ramelteon)

Prescription only

Oleptro (Trazodone)

Prescription only
Helps you fall asleep.

Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.

Improves mood and helps you sleep.

Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.

3.6/ 5 average rating with 59 reviewsforOleptro
Upsides
  • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
  • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
  • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
  • Commonly used in lower doses to help treat sleep problems (insomnia).
  • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
  • Fewer sexual side effects than many other antidepressants.
  • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
  • Comes as a generic medication and is cheaper than many other sleep aides.
  • Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
  • Rozerem (ramelteon) is only available as a brand name.
  • Rozerem (ramelteon) is only available in 1 strength.
  • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
  • Not recommended for children.
  • Rozerem (ramelteon) can't be used if you have sleep apnea.
  • Not as effective as other medications for depression.
  • More sedating than other antidepressants.
  • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
  • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
  • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
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59 reviews so far
73%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle

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Side effects
5possible side effects
  • Dizziness
    4%
  • Sleepiness
    3%
  • Fatigue
    3%
  • Nausea
    3%
  • Worsening insomnia
    3%
See more detailed side effects
29possible side effects
  • Somnolence/Sedation
    46%
  • Drowsiness
    41%
  • Dry Mouth
    34%
  • Headache
    33%
  • Dizziness/Lightheadedness
    28%
  • Dry mouth
    25%
  • Dizziness
    25%
  • Nausea
    21%
  • Blurred Vision
    15%
  • Fatigue
    15%
  • Nausea/Vomiting
    13%
  • Diarrhea
    9%
  • Constipation
    8%
  • Skin Condition/Edema
    7%
  • Weight Loss
    6%
  • Nasal/Sinus Congestion
    6%
  • Abdominal/Gastric Disorder
    6%
  • Syncope
    5%
  • Musculoskeletal Aches/Pains
    5%
  • Tremors
    5%
  • Nightmares/Vivid Dreams
    5%
  • Weight Gain
    5%
  • Back pain
    5%
  • Vision blurred
    5%
  • Sexual dysfunction
    5%
  • Hypotension
    4%
  • Incoordination
    2%
  • Ejaculation disorders
    2%
  • Decreased libido
    2%
See more detailed side effects
Risks and risk factors
  • Severe allergic reaction
  • Behavior changes
  • Sleepiness
  • Breathing problems
    • Alcohol
    • Taking narcotics, tranquilizers, or antihistamines
  • Hormonal changes
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Seizures
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    • Drug interactions
  • Painful erection
  • Low blood pressure
    • Age 65 years or older
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings