Compare Rozerem vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Rozerem
(Ramelteon)

Oleptro
(Trazodone)

Coming soon.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.
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Reviews & ratings
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Reviews for Oleptro (Trazodone)
72%
+72% vs. Rozerem (Ramelteon)
48%
+48% vs. Rozerem (Ramelteon)
24%
24% vs. Rozerem (Ramelteon)
Side effects
RozeremOleptro

We haven’t found good data for Rozerem side effects.

FDA side effect reports for Rozerem »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Blurred vision 11%
  • Nausea 8%
  • Fatigue 7%
  • Skin condition/edema 6%
  • Headache 6%
More Oleptro side effects »
How it works
RozeremOleptro
Coming soon.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
RozeremOleptro
Coming soon.
Antidepressant
Serotonin antagonist and reuptake inhibitor
Prescription only
Available as
RozeremOleptro
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
RozeremOleptro
  • Insomnia
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Rozerem (Ramelteon)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Oleptro (Trazodone)
Risk factors for serious side effects
RozeremOleptro
Coming soon.
  • Age 24 years or younger
  • History of seizures
  • Alcoholism
  • Eating disorder
  • Higher dose
  • Drug interactions
    • Age 65 years or older
    • Alcohol
    • Taking other medicines that make you less alert
    Detailed Oleptro (Trazodone) risks & warnings »
    Pregnancy category
    RozeremOleptro
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    CFDA pregnancy category (Weigh risks vs. benefits)

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    See the FDA package insert
    Alcohol
    No specific alcohol-related info.No specific alcohol-related info.
    Food
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    No specific kidneys and liver-related info.No specific kidneys and liver-related info.
    Sex
    No specific sex-related info.
    • Fewer sexual side effects than many other antidepressants.
    • Seek medical attention for unwanted, persistent erection.
    • Rarely, Oleptro (Trazodone) can cause a painful, persistent erection for 4 hours or more. Seek medical attention.
    Sleep
    No specific sleep-related info.
    • Commonly used in lower doses to help treat sleep problems (insomnia).
    • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
    • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
    • Comes as a generic medication and is cheaper than many other sleep aides.
    Weight
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    RozeremOleptro
    Coming soon.
    • Commonly used in lower doses to help treat sleep problems (insomnia).
    • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
    • Fewer sexual side effects than many other antidepressants.
    • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
    • Comes as a generic medication and is cheaper than many other sleep aides.
    • Six out of ten people who use an antidepressant for the first time find that it works for them.
    Downsides and risks
    RozeremOleptro
    Coming soon.
    • Not as effective as other medications for depression.
    • More sedating than other antidepressants.
    • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
    • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
    • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
    Tips from our pharmacists for people taking the medication
    RozeremOleptro
    Coming soon.
    • Makes you sleepy. Take at bedtime.
    • Can cause temporary dry mouth and upset stomach.
    • Seek medical attention for unwanted, persistent erection.
    • Tell your doctor if you notice sudden mood changes or unusual thoughts.
    Learn more
    More about RozeremSide effectsFDA package insert
    More about OleptroSide effectsReviews & ratingsAlternativesFDA package insert