Compare Sanctura vs. Vesicare

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sanctura
(Trospium)

Vesicare
(Solifenacin)

Coming soon.Treats an overactive bladder. Vesicare (Solifenacin) is a good treatment for overactive bladder and doesn’t have as many side effects as similar medications.
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Reviews & ratings
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Side effects
SancturaVesicare

We haven’t found good data for Sanctura side effects.

FDA side effect reports for Sanctura »
  • Dry mouth 24%
  • Constipation 10%
  • Vision blurred 3%
  • Indigestion 3%
  • Urinary tract infection nos 2%
  • Fatigue 1%
  • Dry eyes nos 1%
  • Flu 1%
  • Abdominal pain upper 1%
  • Nausea 1%
More Vesicare side effects »
How it works
SancturaVesicare
Coming soon.Vesicare (Solifenacin) is an anticholinergic. It relaxes the bladder muscles by lowering muscle spasms. This helps people go to the bathroom less often and better control their urination.
Type of medication
SancturaVesicare
Coming soon.
Antispasmodic
Anticholinergic
Prescription only
Available as
SancturaVesicare
  • Pill
  • Extended release
  • Pill
Used for (click to learn more)
SancturaVesicare
  • Bladder muscle dysfunction - overactive
Risk factors for serious side effects
SancturaVesicare
Coming soon.
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • Outside in hot weather
    • Dehydrated
    • Exercising
      • History of cardiovascular disease
      • Higher dose of Vesicare (Solifenacin) Taking with other medicines that prolong QT interval (heart problems)
      Detailed Vesicare (Solifenacin) risks & warnings »
      Pregnancy category
      SancturaVesicare
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      No specific alcohol-related info.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      Food
      No specific food-related info.
      • Can be taken with or without food.
      • Can be taken with or without food.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.No specific sex-related info.
      Sleep
      No specific sleep-related info.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      • Vesicare (Solifenacin) can cause drowsiness, confusion, dizziness, hallucinations, or blurred vision. Avoid driving, operating machinery, or doing anything that requires you to be alert until you know how Vesicare (Solifenacin) affects you.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      SancturaVesicare
      Coming soon.
      • Vesicare (Solifenacin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
      • Can be taken with or without food.
      • Causes fewer side effects than other medications in the same drug class.
      • Only needs to be taken once a day.
      Downsides and risks
      SancturaVesicare
      Coming soon.
      • Generally not recommended to use in people ages 65 and older since it can cause drowsiness and increase the risk of falls.
      • Can’t be used if you have uncontrolled narrow-angle glaucoma.
      • Not recommended if you have ulcerative colitis or certain other gastrointestinal problems, since Vesicare (Solifenacin) can slow stomach emptying.
      • Has some drug interactions, so make sure your doctor has your complete list of medications.
      • Not available as a generic.
      Tips from our pharmacists for people taking the medication
      SancturaVesicare
      Coming soon.
      • Might cause dry mouth, constipation, drowsiness, dizziness, and blurry vision.
      • To prevent dry mouth, avoid using mouthwashes with alcohol, chew on sugar-free gum, and take small sips of water as needed.
      • Can be taken with or without food.
      • Let your doctor know if your symptoms don’t get better in two weeks. There could be other causes of your bladder problems or you may need to try a different medicine.
      • Can cause drowsiness, so avoid taking with alcohol or other medicines that make you sleepy.
      Learn more
      More about SancturaSide effectsFDA package insert
      More about VesicareSide effectsReviews & ratingsAlternativesFDA package insert