Compare scopolamine vs. Compro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Prevents nausea and vomiting.

Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.

3.9/ 5 average rating with 26 reviewsforscopolamine
Helps you feel less queasy.

Compro (Prochlorperazine) can be used to treat severe nausea and vomiting and can be taken orally or rectally, but get ready for a nap.

3.0/ 5 average rating with 20 reviewsforCompro
Upsides
  • Transderm-Scop (scopolamine) is well tolerated.
  • Prevents nausea for 3 days.
  • Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
  • Available in generic, so it's cheap.
  • Can be taken by mouth, as a shot, or rectally.
  • Can take anywhere from 10 minutes (by shot) to 60 minutes (rectally) to start working.
Downsides
  • Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
  • The side effects can be worse if you are 65 and older.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
  • You're more likely to have heat stroke or feel dehydrated.
  • It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
  • Can make you really drowsy. Drinking alcohol with it can make the drowsiness even worse.
  • Can't be used by people over 65 because they can be more affected by the side effects.
  • It can make you more likely to get heatstroke.
Used for
Dosage forms
  • Patch
  • Pill
  • Suppository
Price
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Reviews
26 reviews so far
73%
saidit'sworth it
58%
saiditworked well
19%
saidit'sa big hassle

Have you used Transderm-Scop (scopolamine)?

Leave a review
20 reviews so far
45%
saidit'sworth it
35%
saiditworked well
35%
saidit'sa big hassle

Have you used Compro (Prochlorperazine)?

Leave a review
Side effects
The Transderm-Scop (scopolamine) FDA package insert doesn’t have numbers about how common side effects are.
The Compro (Prochlorperazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased pressure in the eyes
    • Open angle glaucoma
  • Worsening stomach, bowel, or bladder blockages
    • Blockages in the stomach, bowels or bladder
  • Skin burns
    • MRI examination
  • Heat stroke
  • Worsening seizures or psychosis
    • History of seizures
    • History of psychosis
  • Sleepiness and dizziness
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Increased risk of death
    • Over age 65
    • Dementia
    • Taking antipsychotics
  • Seizures
    • History of seizures
  • Involuntary muscle movements
    • Age over 65
  • Neuroleptic malignant syndrome
  • Heatstroke
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings