Compare Seroquel vs. fluphenazine decanoate

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Seroquel (quetiapine)

Prescription only
Helps control your thoughts and mood.

Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.

5.0/ 7 average rating with 250 reviewsforSeroquel
Treats schizophrenia or psychosis.

Prolixin Decanoate (fluphenazine decanoate) is long-acting medicine for stabilizing your mood that must be given by a trained healthcare professional.

  • Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
  • Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
  • Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
  • Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • Can be given less frequently than the oral, short-acting version.
  • Available in generic.
  • Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
  • You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can only be used if you're already stable on the short-acting version of this medicine.
Used for
Dosage forms
  • Pill
  • Extended release
  • Injection
Lowest price near you
Find instant savings
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
think this treatment is worth it
think this treatment works well
think this treatment is a hassle

Have you used Seroquel (quetiapine)?

Leave a review
Not enough review data.Leave a review
Side effects
10possible side effects
  • Drowsiness
  • Dry mouth
  • Headache
  • Weakness
  • Constipation
  • Dizziness
  • Tremor
  • Stomach pain
  • Low blood pressure
  • Agitation
See more detailed side effects
The Prolixin Decanoate (fluphenazine decanoate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Higher risk of death

    Elderly patients with dementia-related psychosis

  • Suicidal thoughts or behavior

    Children, adolescents, and young adults (<24 years old)

  • Heart problems

    History of heart problems

    ...and 1 more risk factors

  • Metabolic changes (increased blood sugar, high cholesterol and weight gain)

    People with diabetes

    ...and 1 more risk factors

See more detailed risks and warnings
  • Increased risk of death

    People over 65 with dementia and psychosis

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

See more detailed risks and warnings