Compare Simbrinza vs. Pilocarpine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Simbrinza
(Brinzolamide / Brimonidine)

Salagen
(Pilocarpine)

lowers eye pressure Simbrinza ia an effective two medicine combination that is used when one medication alone is not effective, and you are looking for ease of using both medications in one drop.lowers eye pressure A very effective first line treatment for increased eye pressure. Lowering eye pressure back to normal may prevent the onset of glaucoma.
Reviews & ratings
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Have you used Simbrinza (Brinzolamide / Brimonidine)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Salagen (Pilocarpine)?
Worth itNot sureNot worth it
Side effects
SimbrinzaPilocarpine

We haven’t found good data for Simbrinza side effects.

FDA side effect reports for Simbrinza »

We haven’t found good data for Pilocarpine side effects.

FDA side effect reports for Pilocarpine »
How it works
SimbrinzaPilocarpine
Simbrinza decreases the production of fluids within the eye, and increases the flow of fluids out of the eye.pilocarpine increases the flow of fluids out of the inner eye.
Type of medication
SimbrinzaPilocarpine
No lower cost generic availableLower-cost generic available
Available as
SimbrinzaPilocarpine
  • Eye drops
  • Eye drops
Used for
SimbrinzaPilocarpine
  • Ocular Hypertension Open Angle Glaucoma
  • Head And Neck Cancer Radiation Induced Xerostomia Raised Intraocular Pressure Sjogrens Syndrome Xerostomia
Risk factors for serious side effects
SimbrinzaPilocarpine
    Coming soon.
      Coming soon.
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Upsides and benefits
      SimbrinzaPilocarpine
      • Simbrinza may be more effective because it contains two medications
      • It is easier to take two medications in one drop.
      • pilocarpine is often used with other drugs to control eye pressure.
      Downsides and risks
      SimbrinzaPilocarpine
      • Simbrinza may cause carbonated beverages to taste metallic..
      • You must wait 5 minutes before using another eye drop
      • Remove contact lenses and leave out for 15 minutes after using the the eyedrop
      • Not used in children under 2 years of age
      • pilocarpine causes the pupil of the eye to become smaller, and may cause dim vision, especially at night, therefore driving at night may be impaired.
      Tips from our pharmacists for people taking the medication
      SimbrinzaPilocarpine
      • Wash hands before putting drops in eyes.
      • Do not touch the dropper tip to your eye or hands.
      • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
      • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
      • Wash hands before putting drops in eyes.
      • Do not touch the dropper tip to your eye or hands.
      • If you wear contacts remove them and wait 15 minutes, after putting the drop in eye, to replace them.
      • After instilling drops in the eye, press one finger to the inner corner of eye, by the nose, and press lightly for 1 minute.
      Learn more
      More about SimbrinzaSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Simbrinza (Brinzolamide / Brimonidine)?
      Worth itNot sureNot worth it
      More about PilocarpineSide effectsAlternativesFDA package insert
      Have you used Salagen (Pilocarpine)?
      Worth itNot sureNot worth it