Compare simvastatin vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zocor (simvastatin)

Prescription only
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

3.8/ 5 average rating with 1176 reviewsforsimvastatin
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

2.9/ 5 average rating with 68 reviewsforTrilipix
Upsides
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
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Reviews
1176 reviews so far
61%
saidit'sworth it
48%
saiditworked well
14%
saidit'sa big hassle

Have you used Zocor (simvastatin)?

Leave a review
68 reviews so far
50%
saidit'sworth it
22%
saiditworked well
25%
saidit'sa big hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
Side effects
The Zocor (simvastatin) FDA package insert doesn’t have numbers about how common side effects are.
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Muscle pain and kidney damage
    • Kidney disease
    • High dose of Zocor (simvastatin)
    • Combining Zocor (simvastatin) with other cholesterol-lowering drugs
    • Older age
    • Female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to unborn baby
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Certain drugs can increase the dose of Zocor (simvastatin) in the body
  • High blood sugar
    • History of high blood sugar
See more detailed risks and warnings
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings