Compare Singulair vs. Flovent

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Flovent Diskus

Prevents breathing problems. Singulair (Montelukast) has fewer side effects but doesn't work as well as steroid inhalers for asthma. It also helps with allergies.Prevents breathing problems. Flovent Diskus (Fluticasone) is good at controlling and preventing asthma symptoms when you take it every day.
How it works
Singulair (Montelukast) is a leukotriene inhibitor. It lowers inflammation in your lungs and nasal passages to prevent asthma and relieve allergies.Flovent Diskus (Fluticasone) is a corticosteroid. It lowers inflammation in your lungs, which controls asthma and prevents asthma attacks.
Type of medication
Leukotriene modifier
Prescription only
Prescription only
Available as
  • Pill
  • Chewable tablet
  • Granule
  • Inhaler
Used for (click to learn more)
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
Reviews for Singulair (Montelukast)
of people say Singulair (Montelukast) is worth it
say it works well
say it's a big hassle
Reviews for Flovent Diskus (Fluticasone)
+2% vs. Singulair (Montelukast)
7% vs. Singulair (Montelukast)
+4% vs. Singulair (Montelukast)
Side effects
  • Dizziness 1%
  • Muscle weakness/fatiguea/fatigue 1%
  • Decreased liver function 1%
  • Congestion, nasal 1%
  • Pain, dental 1%
More Singulair side effects »
  • Throat irritation 14%
  • Bronchitis 7%
  • Headache 7%
  • Ear, nose, or throat infection 5%
  • Sinusitis/sinus infection 4%
  • Viral gastrointestinal infection 4%
  • Muscle injury 4%
  • Nausea and vomiting 4%
  • Fever 3%
  • Viral infection 3%
More Flovent side effects »
Risk factors for serious side effects
  • Exercise-induced asthma
  • Other environmental triggers
    • Recent treatment with corticosteroid medication
    • Lowering dose of corticosteroid medication
    • History of phenylketonuria (PKU)
    • History of liver disease including hepatitis
    • history of alcohol use
    • Other medications that cause liver injury
    Detailed Singulair (Montelukast) risks & warnings »
    • Lowering dose or stopping too quickly especially after long-term treatment
    • Stress such as trauma, surgery or infection
    • Severe milk protein allergy
    • Bacterial or viral infection not being treated
    • Long-term treatment with Flovent Diskus (Fluticasone)
    • Not vaccinated against chickenpox or measles
      • Dose of Flovent Diskus (Fluticasone)
      • Duration of treatment
      • Not rinsing mouth after use
      • Using higher dose of Flovent Diskus (Fluticasone)
      • History of high internal eye pressure
      • History of cataracts
      • History of glaucoma
      Detailed Flovent Diskus (Fluticasone) risks & warnings »
      Pregnancy category
      • There are reports of liver injury in people taking Singulair (Montelukast) mostly in combination with other factors such as drugs, alcohol, and liver disease. If you have any of these risk factors, your doctor will need to check your liver function periodically.
      No specific alcohol-related info.
      • Granules can be taken by mouth or dissolved in liquid or soft food.
      No specific food-related info.
      Kidneys and liver
      No specific kidneys and liver-related info.No specific kidneys and liver-related info.
      No specific sex-related info.No specific sex-related info.
      • Can cause behavior changes, agitation, aggression, and difficulty sleeping for some people.
      • Rare cases of behavior changes occur in adults and children taking Singulair (Montelukast). Symptoms range from irritability and memory problems to hallucinations and suicidal thinking. It is not clear if this is linked to history of these conditions. Get medical help immediately if you notice symptoms of agitation, aggression, sleep disturbance, or suicidal thoughts while taking Singulair (Montelukast).
      No specific sleep-related info.
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      • Prevents symptoms and improves lung function in children and adults with chronic asthma.
      • A single 10 mg dose improves exercise-induced asthma symptoms for up to 24 hours.
      • Fewer side effects compared to other asthma treatments.
      • Also relieves nasal allergy symptoms.
      • Effective pill alternative to corticosteroid inhalers.
      • Relieves symptoms and improves control of asthma.
      • People report fewer asthma symptoms and better lung function when they take it every day.
      • Inhaling this medicine (rather than taking an oral steroid) gets more into the lungs and less into rest of your body, which lowers the risk of side effects. Inhaled corticosteroids can be used safely for years compared to oral corticosteroids like prednisone.
      • Available as both an inhaler and Diskus device.
      Downsides and risks
      • You have to use Montelukast every day to control your symptoms.
      • Somewhat less effective than corticosteroid inhalers for asthma.
      • There's no generic available, so it can be expensive.
      • Can cause behavior changes, agitation, aggression, and difficulty sleeping for some people.
      • You have to use Fluticasone every day to control your symptoms.
      • You can't lower the dose or stop taking it too suddenly.
      • Steroids can slow height growth in kids.
      • Because steroids suppress your immune system, you can catch bacterial and viral infections easier, and they can take longer to go away.
      • Can cause new or worsening eye pressure, glaucoma, and cataracts.
      Tips from our pharmacists for people taking the medication
      • Take it once a day to control asthma and allergy symptoms.
      • If you're using it for asthma or allergies, take it in the evening.
      • Use it 2 hours before exercising.
      • Granules can be taken by mouth or dissolved in liquid or soft food.
      • Doesn't treat sudden wheezing or asthma attacks once they start. Keep a fast-acting (rescue) inhaler with you.
      • The chewable tablets contain aspartame, so don't use them if you have a sensitivity to phenylalanine or phenylketones.
      • Use it every day to control your asthma symptoms.
      • Can take 2 weeks or more to feel full effects.
      • Pump the inhaler 4 times before your first dose, or if it's been more than 7 days since your last dose.
      • Wait at least 1 minute between doses.
      • Rinse your out mouth with water after each use.
      • Hold your breath for 10 seconds after using Advair Diskus.
      • Don't breathe out into the inhaler mouthpiece.
      • Tell your doctor if the medication stops working or if your symptoms get worse.
      • Diskus contains lactose, so don't use it if you're allergic to milk protein.
      Learn more
      More about SingulairSide effectsReviews & ratingsAlternativesFDA package insert
      More about FloventSide effectsReviews & ratingsAlternativesFDA package insert