Compare Soma vs. baclofen

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Soma (carisoprodol)

Prescription only

Lioresal (baclofen)

Prescription only
Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

4.7/ 7 average rating with 220 reviewsforSoma
Relaxes your muscles.

Lioresal (baclofen) is a first choice treatment for muscle spasticity caused by multiple sclerosis or spinal cord injuries, but it's not recommended for other types of muscle spasms.

4.8/ 7 average rating with 33 reviewsforbaclofen
Upsides
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
  • A better option for seniors compared to other muscle relaxants since it has fewer side effects than other similar medicines.
  • Lioresal (baclofen) is available as a generic and is a relatively inexpensive medication.
Downsides
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
  • Except for specific muscle spasms caused by brain injury or multiple sclerosis, Lioresal (baclofen) is not a recommended medicine.
  • If you've been taking Lioresal (baclofen) regularly for a long time, you'll need to get off of it slowly.
  • Lioresal (baclofen) can make you sleepy.
  • If you've had a stroke, Lioresal (baclofen) may not work as well, and you're more likely to experience side effects.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$12.75
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$9.99
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Reviews
220 
61%
think this treatment is worth it
39%
think this treatment works well
9%
think this treatment is a hassle

Have you used Soma (carisoprodol)?

Leave a review
33 
61%
think this treatment is worth it
55%
think this treatment works well
15%
think this treatment is a hassle

Have you used Lioresal (baclofen)?

Leave a review
Side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
1possible side effects
  • Drowsiness
    63%
See more detailed side effects
Risks and warnings
  • Sleepiness and dizziness

    Taking other medications that also cause sleepiness

    ...and 3 more risk factors

  • Abuse, dependence and withdrawal

    Prior history of drug abuse

    ...and 1 more risk factors

  • Seizures

    Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol

See more detailed risks and warnings
  • Withdrawal symptoms

    Stopping Lioresal (baclofen) too quickly

  • Driving impairment

    Taking with alcohol

    ...and 2 more risk factors

  • Seizures

    Higher dose

    ...and 5 more risk factors

See more detailed risks and warnings