Compare Soma vs. Skelaxin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

3.5/ 5 average rating with 220 reviewsforSoma
Relaxes your muscles.

Skelaxin (metaxalone) is used for muscle spasms and musculoskeletal pain with mixed results.

Upsides
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
  • Can be used for muscle spasms and muscle pain if other medications have not worked.
  • Available as generic.
  • Slightly less sedation and side effects compared to other muscle relaxants.
Downsides
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
  • Effects don't last that long. You need to take Skelaxin (metaxalone) up to 3-4 times daily.
  • Several studies showed mixed results when Skelaxin (metaxalone) was compared with a sugar pill for treatment of muscle spasms and musculoskeletal pain.
  • Can make you very drowsy or sleepy
  • Even though a generic is available, it is still fairly expensive.
Used for
  • Musculoskeletal pain
Dosage forms
  • Pill
  • Pill
Price
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Reviews
220 reviews so far
61%
saidit'sworth it
39%
saiditworked well
9%
saidit'sa big hassle

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Side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
The Skelaxin (metaxalone) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
    • Elderly
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
    • Taking Soma (carisoprodol) for a long time
  • Seizures
    • Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol
See more detailed risks and warnings
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
  • Serotonin syndrome
    • Taking antidepressants
    • Higher than recommended doses of Skelaxin (metaxalone)
  • Liver damage
    • History of liver disease
  • Liver or Kidney problems
    • History of liver disease
    • History of kidney disease
See more detailed risks and warnings