Compare Soma vs. Zanaflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Soma (carisoprodol)

Prescription only

Zanaflex (tizanidine)

Prescription only
Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

3.5/ 5 average rating with 220 reviewsforSoma
Relaxes your muscles.

Zanaflex (tizanidine) isn't a first-choice treatment for muscle spasticity. Try other options before using this.

4.3/ 5 average rating with 26 reviewsforZanaflex
Upsides
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
  • Relieves muscle spasticity.
  • Available as a generic.
  • Available in a tablet or capsule form. It also comes in a capsule that can be opened and sprinkled in applesauce for people that can't swallow pills.
Downsides
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
  • This isn't a first-choice muscle relaxing medication. Other drugs work better and have fewer side effects.
  • Takes over an hour to kick in and only lasts 3 to 6 hours.
  • Zanaflex (tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication.
  • Need to be consistent every day in taking this with or without food.
  • Elderly individuals have more side effects when taking Zanaflex (tizanidine).
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
220 reviews so far
61%
saidit'sworth it
39%
saiditworked well
9%
saidit'sa big hassle

Have you used Soma (carisoprodol)?

Leave a review
26 reviews so far
81%
saidit'sworth it
73%
saiditworked well
19%
saidit'sa big hassle

Have you used Zanaflex (tizanidine)?

Leave a review
Side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
17possible side effects
  • Dry mouth
    49%
  • Sleepiness
    48%
  • Weakness
    41%
  • Dizziness
    16%
  • Urinary tract infection
    10%
  • General infection
    6%
  • Liver test abnormality
    6%
  • Constipation
    4%
  • Vomiting
    3%
  • Speech disorder
    3%
  • Blurred vision
    3%
  • Urinary frequency
    3%
  • Flu syndrome
    3%
  • Involuntary muscle movement
    3%
  • Nervousness
    3%
  • Sore throat
    3%
  • Hay fever
    3%
See more detailed side effects
Risks and risk factors
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
    • Elderly
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
    • Taking Soma (carisoprodol) for a long time
  • Seizures
    • Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol
See more detailed risks and warnings
  • Liver damage
    • Taking maximum doses of Zanaflex (tizanidine)
  • Dizziness and low blood pressure
    • Age 65 years or older
    • Currently on blood pressure control medications
  • Sleepiness and driving impairment
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
    • Elderly
  • Withdrawal side effects
    • Stopping Zanaflex (tizanidine) suddenly
See more detailed risks and warnings