Compare Soma vs. Zanaflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Soma
(carisoprodol)

Zanaflex
(tizanidine)

Relaxes your muscles. Soma (Carisoprodol) is widely used to treat muscle spasms and is available as a generic, but it's not considered a first-choice treatment for muscle spasms. It's also not meant for long-term therapy.Relaxes your muscles. Zanaflex (Tizanidine) isn't a first-choice treatment for muscle spasms. Try other options before using this.
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Coupons for Soma
Best available price for 90 (350mg) tablets of carisoprodol
Coupons for Zanaflex
Best available price for 90 (4mg) tablets of tizanidine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.74Soma
Reviews for Soma (carisoprodol)
61%
of people (All ages) say Soma (carisoprodol) is worth it
39%
say it works well
9%
say it's a big hassle
220 reviews
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it
Reviews for Zanaflex (tizanidine)
81%
+20% better vs. Soma (carisoprodol)
73%
+34% better vs. Soma (carisoprodol)
19%
-10% worse vs. Soma (carisoprodol)
Have you used Zanaflex (tizanidine)?
Worth itNot sureNot worth it
Side effects
SomaZanaflex
  • Drowsiness 7%
  • Dizziness 6%
  • Hedache 3%
  • Central nervous system reactions 2%
More Soma side effects »

We haven’t found good data for Zanaflex side effects.

FDA side effect reports for Zanaflex »
How it works
SomaZanaflex
Soma (Carisoprodol) is a muscle relaxant. It works in the brain to help calm down muscle spasms.Zanaflex (Tizanidine) is a muscle relaxer. It works in the nervous system to calm down muscle spasms without interfering with normal muscle function.
Type of medication
SomaZanaflex
Prescription only
Prescription only
Available as
SomaZanaflex
  • Pill
  • Pill
Used for
SomaZanaflex
Risk factors for serious side effects
SomaZanaflex
  • Taking other medications that also cause sleepiness
  • Recreational drug use
  • Excessive alcohol use
  • Prior history of drug abuse
  • Prior history of overdoses of drugs of abuse, recreational drugs or alcohol
Detailed Soma (carisoprodol) risks & warnings »
  • Age 65 years or older
  • Taking with alcohol
  • Taking other medicines that make you less alert
  • Age 65 or greater
Detailed Zanaflex (tizanidine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
SomaZanaflex
  • Don't drink alcohol while on this medication.
  • Don't drink alcohol while using this.
Food
SomaZanaflex
No food related info.
  • Can be taken with or without food, but you need to be consistent in how you take it every day.
  • Need to be consistent every day in taking this with or without food.
  • Can be taken with or without food, but you need to be consistent since food affects how the medication is absorbed and works.
Pain
SomaZanaflex
  • Can cause stomach pain, nausea and vomiting.
No pain related info.
Sleep
SomaZanaflex
No sleep related info.
  • Can cause dizziness, fatigue, drowsiness, and dry mouth.
  • Can cause extreme drowsiness or dizziness if you are taking meds for high blood pressure.
Upsides and benefits
SomaZanaflex
  • Available in generic.
  • Available in two different strengths, although the smaller strength is only available as brand name and thus more expensive.
  • Relieves muscle spasms well.
  • Can be taken with or without food, but you need to be consistent in how you take it every day.
  • Available as a generic.
  • Available in a tablet or capsule form. It also comes in a capsule that can be opened and sprinkled in applesauce for people that can't swallow pills.
Downsides and risks
SomaZanaflex
  • Not first line for treating muscle spasms.
  • Can cause dizziness and sleepiness.
  • Not meant for long term therapy.
  • Can cause dependence and withdrawal symptoms if you stop taking it suddenly.
  • This isn't a first-choice muscle relaxing medication. Other drugs work better and have fewer side effects.
  • Zanaflex (Tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication.
  • Need to be consistent every day in taking this with or without food.
  • Elderly individuals have more side effects when taking Zanaflex (Tizanidine).
  • Can't stop taking this abruptly if you use it regularly.
Tips from our pharmacists for people taking the medication
SomaZanaflex
  • Can cause dizziness, fatigue, and sleepiness.
  • Take the medication at the same time each day.
  • Not to be used for long-term treatment (2 to 3 weeks maximum)
  • Don't drink alcohol while on this medication.
  • Can cause stomach pain, nausea and vomiting.
  • Can cause dizziness, fatigue, drowsiness, and dry mouth.
  • Avoid activities requiring mental alertness (like driving) until you know how it affects you.
  • Can cause extreme drowsiness or dizziness if you are taking meds for high blood pressure.
  • Side effects are more prevalent in the elderly.
  • Don't drink alcohol while using this.
  • Can be taken with or without food, but you need to be consistent since food affects how the medication is absorbed and works.
Learn more
More about SomaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Soma (carisoprodol)?
Worth itNot sureNot worth it
More about ZanaflexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Zanaflex (tizanidine)?
Worth itNot sureNot worth it