Compare Sonata vs. Hetlioz

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sonata (Zaleplon)

Prescription only

Hetlioz (tasimelteon)

Prescription only
Helps you sleep.

Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.

2.9/ 5 average rating with 175 reviewsforSonata
Keeps the sleep cycle normal for completely blind people who aren't able to see light.

Hetlioz (tasimelteon) is the only approved medicine to help completely blind people who are unable to see light maintain regular sleep cycles. It is only available as a brand name, so it can be expensive.

Upsides
  • Effective at helping people fall asleep faster.
  • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
  • Hetlioz (tasimelteon) is not addictive.
  • Hetlioz (tasimelteon) is the only drug that's approved to help people unable to see light to have regular sleep cycles.
  • If you have to stop taking Hetlioz (tasimelteon) suddenly, you're not likely to have withdrawal.
Downsides
  • Not typically used for long-term treatment since it can be habit-forming.
  • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
  • Interacts badly with many other medications.
  • Not a good option if you're pregnant or breast-feeding.
  • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
  • Hetlioz (tasimelteon) can take weeks to months for you to notice any effect.
  • Hetlioz (tasimelteon) is only available as a brand name so it can be expensive.
Used for
  • Non-24 hour sleep-wake cycle
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$13611.60
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Reviews
175 reviews so far
42%
saidit'sworth it
23%
saiditworked well
27%
saidit'sa big hassle

Have you used Sonata (Zaleplon)?

Leave a review
Not enough review data.Leave a review
Side effects
18possible side effects
  • Headache
    42%
  • Dizziness
    9%
  • Nausea
    8%
  • Asthenia
    7%
  • Abdominal Pain
    6%
  • Somnolence
    6%
  • Amnesia
    4%
  • Dysmenorrhea
    4%
  • Paresthesia
    3%
  • Eye pain
    3%
  • Malaise
    2%
  • Anorexia
    2%
  • Depersonalization
    2%
  • Hypesthesia
    2%
  • Tremor
    2%
  • Abnormal Vision
    2%
  • Hyperacusis
    2%
  • Parosmia
    2%
See more detailed side effects
5possible side effects
  • Headache
    17%
  • Abnormal liver tests
    10%
  • Nightmares or abnormal dreams
    10%
  • Common cold or flu
    7%
  • Urinary tract infection
    7%
See more detailed side effects
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
    • Less than 7 hours of sleep
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Sleep driving
    • Taking with alcohol or drugs
  • Serious allergic reactions
  • Risk to fetus
    • Women of childbearing age
    • Breast-feeding
See more detailed risks and warnings