Compare Sonata vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sonata
(Zaleplon)

Oleptro
(Trazodone)

Helps you sleep. Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
3.810344827586207Sonata
Reviews for Sonata (Zaleplon)
42%
of people say Sonata (Zaleplon) is worth it
24%
say it works well
27%
say it's a big hassle
Reviews for Oleptro (Trazodone)
72%
+30% vs. Sonata (Zaleplon)
48%
+24% vs. Sonata (Zaleplon)
24%
+3% vs. Sonata (Zaleplon)
Side effects
SonataOleptro
  • Headache 7%
  • Abdominal pain 3%
  • Amnesia 3%
  • Muscle weakness 2%
  • Eye pain 2%
  • Menstrual cramps 2%
  • Drowsiness 2%
  • Tingling sensation 2%
  • Dizziness 2%
  • Tremor 1%
More Sonata side effects »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Blurred vision 11%
  • Nausea 8%
  • Fatigue 7%
  • Skin condition/edema 6%
  • Headache 6%
More Oleptro side effects »
How it works
SonataOleptro
Sonata (Zaleplon) is in a class of drugs called sedative-hypnotics. Researchers don't know exactly how it works, but it interacts with your brain to make you relaxed and sleepy.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
SonataOleptro
SedativePrescription only
Antidepressant
Serotonin antagonist and reuptake inhibitor
Prescription only
Available as
SonataOleptro
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
SonataOleptro
How well it works for depression
The free Iodine Start program helps people track how well they are improving, and find the right antidepressant faster.
The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Sonata (Zaleplon)The free Iodine Start program (personal reports and coaching) is currently only for antidepressants. For now, you can read our pharmacist info about this medication.Learn more about Oleptro (Trazodone)
Risk factors for serious side effects
SonataOleptro
  • Continuous use for 2 weeks or more
  • Alcohol
  • Taking other medicines that make you less alert
  • Less than 7 hours of sleep
  • Undiagnosed psychiatric conditions
  • Taking with alcohol or drugs
    • Women of childbearing age
    • Breast-feeding
    Detailed Sonata (Zaleplon) risks & warnings »
    • Age 24 years or younger
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    • Drug interactions
      • Age 65 years or older
      • Alcohol
      • Taking other medicines that make you less alert
      Detailed Oleptro (Trazodone) risks & warnings »
      Pregnancy category
      SonataOleptro
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      CFDA pregnancy category (Weigh risks vs. benefits)

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      See the FDA package insert
      Alcohol
      • It works best if taken without food and avoid taking it with alcohol or drugs.
      • Sonata (Zaleplon) can be disinhibiting (like alcohol) or cause hallucinations. Tell your doctor if you notice any unusual changes in behavior.
      No specific alcohol-related info.
      Food
      • It works best if taken without food and avoid taking it with alcohol or drugs.
      No specific food-related info.
      Kidneys and liver
      • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
      No specific kidneys and liver-related info.
      Sex
      No specific sex-related info.
      • Fewer sexual side effects than many other antidepressants.
      • Seek medical attention for unwanted, persistent erection.
      • Rarely, Oleptro (Trazodone) can cause a painful, persistent erection for 4 hours or more. Seek medical attention.
      Sleep
      • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
      • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
      • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
      • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
      • Only take it if you have time to sleep for at least 7 hours.
      • Can cause headache, drowsiness, or dizziness.
      • All prescription sleep-aid medicines like Sonata (Zaleplon) have a risk of physical dependence. Dependence means that you'll feel withdrawal symptoms if you stop taking the medication all at once. Talk to your doctor about natural ways to improve sleep or treat underlying conditions that prevent sleep.
      • Sonata (Zaleplon) increases your risk of performing potentially dangerous activities while asleep, such as sleep-walking, sleep-driving, and sleep-eating. Talk to your doctor immediately about stopping Sonata (Zaleplon) if any sleep-related activities occur.
      • Commonly used in lower doses to help treat sleep problems (insomnia).
      • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
      • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
      • Comes as a generic medication and is cheaper than many other sleep aides.
      Weight
      No specific weight-related info.No specific weight-related info.
      Upsides and benefits
      SonataOleptro
      • Effective at helping people fall asleep faster.
      • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
      • Commonly used in lower doses to help treat sleep problems (insomnia).
      • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
      • Fewer sexual side effects than many other antidepressants.
      • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
      • Comes as a generic medication and is cheaper than many other sleep aides.
      • Six out of ten people who use an antidepressant for the first time find that it works for them.
      Downsides and risks
      SonataOleptro
      • Not typically used for long-term treatment since it can be habit-forming.
      • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
      • Interacts badly with many other medications.
      • Not a good option if you're pregnant or breast-feeding.
      • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
      • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
      • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
      • Not as effective as other medications for depression.
      • More sedating than other antidepressants.
      • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
      • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
      • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
      Tips from our pharmacists for people taking the medication
      SonataOleptro
      • Take 30 to 45 minutes before bedtime.
      • Only take it if you have time to sleep for at least 7 hours.
      • It's very addictive and meant for short-term treatment. Dependence can start to form after using it daily for 2 weeks.
      • Can cause headache, drowsiness, or dizziness.
      • It works best if taken without food and avoid taking it with alcohol or drugs.
      • Withdrawal symptoms usually get better in 1 to 2 days.
      • Tell your doctor about any sudden confusion or changes in thoughts or behavior.
      • Makes you sleepy. Take at bedtime.
      • Can cause temporary dry mouth and upset stomach.
      • Seek medical attention for unwanted, persistent erection.
      • Tell your doctor if you notice sudden mood changes or unusual thoughts.
      Learn more
      More about SonataSide effectsReviews & ratingsAlternativesFDA package insert
      More about OleptroSide effectsReviews & ratingsAlternativesFDA package insert