Compare Sonata vs. Oleptro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sonata
(Zaleplon)

Oleptro
(Trazodone)

Helps you sleep. Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.Improves mood and helps you sleep. Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.810344827586207Sonata
Reviews for Sonata (Zaleplon)
42%
of people (All ages) say Sonata (Zaleplon) is worth it
24%
say it works well
27%
say it's a big hassle
174 reviews
Have you used Sonata (Zaleplon)?
Worth itNot sureNot worth it
Reviews for Oleptro (Trazodone)
72%
+30% vs. Sonata (Zaleplon)
48%
+24% vs. Sonata (Zaleplon)
24%
+3% vs. Sonata (Zaleplon)
Have you used Oleptro (Trazodone)?
Worth itNot sureNot worth it
Side effects
SonataOleptro
  • Headache 7%
  • Abdominal pain 3%
  • Amnesia 3%
  • Muscle weakness 2%
  • Eye pain 2%
  • Menstrual cramps 2%
  • Drowsiness 2%
  • Tingling sensation 2%
  • Dizziness 2%
  • Tremor 1%
More Sonata side effects »
  • Somnolence/sedation 27%
  • Drowsiness 21%
  • Dry mouth 14%
  • Dizziness/lightheadedness 13%
  • Dizziness 13%
  • Blurred vision 11%
  • Nausea 8%
  • Fatigue 7%
  • Skin condition/edema 6%
  • Headache 6%
More Oleptro side effects »
How it works
SonataOleptro
Sonata (Zaleplon) is in a class of drugs called sedative-hypnotics. Researchers don't know exactly how it works, but it interacts with your brain to make you relaxed and sleepy.Oleptro (Trazodone) is a serotonin reuptake inhibitor (SRI) antidepressant. It increases serotonin activity in the brain, which regulates mood.
Type of medication
SonataOleptro
SedativePrescription only
Antidepressant
Serotonin antagonist and reuptake inhibitor
Prescription only
Available as
SonataOleptro
  • Pill
  • Pill
  • Extended release
Used for (click to learn more)
SonataOleptro
Risk factors for serious side effects
SonataOleptro
  • Continuous use for 2 weeks or more
  • Alcohol
  • Taking other medicines that make you less alert
  • Less than 7 hours of sleep
  • Undiagnosed psychiatric conditions
  • Taking with alcohol or drugs
    • Women of childbearing age
    • Breast-feeding
    Detailed Sonata (Zaleplon) risks & warnings »
    • Age 24 years or younger
    • History of seizures
    • Alcoholism
    • Eating disorder
    • Higher dose
    • Drug interactions
      • Age 65 years or older
      • Alcohol
      • Taking other medicines that make you less alert
      Detailed Oleptro (Trazodone) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Interactions
      SonataOleptro
      • Interacts badly with many other medications.
      No interactions related info.
      Alcohol
      SonataOleptro
      • It works best if taken without food and avoid taking it with alcohol or drugs.
      No alcohol related info.
      Kidneys and liver
      SonataOleptro
      • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
      No kidneys and liver related info.
      Sleep
      SonataOleptro
      • Effective at helping people fall asleep faster.
      • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
      • Only take it if you have time to sleep for at least 7 hours.
      • Can cause headache, drowsiness, or dizziness.
      No sleep related info.
      Upsides and benefits
      SonataOleptro
      • Effective at helping people fall asleep faster.
      • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
      • Commonly used in lower doses to help treat sleep problems (insomnia).
      • Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
      • Fewer sexual side effects than many other antidepressants.
      • Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
      • Comes as a generic medication and is cheaper than many other sleep aides.
      • Six out of ten people who use an antidepressant for the first time find that it works for them.
      Downsides and risks
      SonataOleptro
      • Not typically used for long-term treatment since it can be habit-forming.
      • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
      • Interacts badly with many other medications.
      • Not a good option if you're pregnant or breast-feeding.
      • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
      • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
      • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
      • Not as effective as other medications for depression.
      • More sedating than other antidepressants.
      • Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
      • Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
      • The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
      Tips from our pharmacists for people taking the medication
      SonataOleptro
      • Take 30 to 45 minutes before bedtime.
      • Only take it if you have time to sleep for at least 7 hours.
      • It's very addictive and meant for short-term treatment. Dependence can start to form after using it daily for 2 weeks.
      • Can cause headache, drowsiness, or dizziness.
      • It works best if taken without food and avoid taking it with alcohol or drugs.
      • Withdrawal symptoms usually get better in 1 to 2 days.
      • Tell your doctor about any sudden confusion or changes in thoughts or behavior.
      • Makes you sleepy. Take at bedtime.
      • Can cause temporary dry mouth and upset stomach.
      • Seek medical attention for unwanted, persistent erection.
      • Tell your doctor if you notice sudden mood changes or unusual thoughts.
      Learn more
      More about SonataSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Sonata (Zaleplon)?
      Worth itNot sureNot worth it
      More about OleptroSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Oleptro (Trazodone)?
      Worth itNot sureNot worth it