Compare Sonata vs. Remeron

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sonata (Zaleplon)

Prescription only

Remeron (mirtazapine)

Prescription only
Helps you sleep.

Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.

3.8/ 7 average rating with 175 reviewsforSonata
Improves mood.

Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.

4.5/ 7 average rating with 152 reviewsforRemeron
Upsides
  • Effective at helping people fall asleep faster.
  • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
Downsides
  • Not typically used for long-term treatment since it can be habit-forming.
  • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
  • Interacts badly with many other medications.
  • Not a good option if you're pregnant or breast-feeding.
  • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
Price
Lowest price near you
$16.93
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$10
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Reviews
175 
42%
think this treatment is worth it
23%
think this treatment works well
27%
think this treatment is a hassle

Have you used Sonata (Zaleplon)?

Leave a review
152 
45%
think this treatment is worth it
39%
think this treatment works well
26%
think this treatment is a hassle

Have you used Remeron (mirtazapine)?

Leave a review
Side effects
10possible side effects
  • Headache
    42%
  • Dizziness
    9%
  • Nausea
    8%
  • Asthenia
    7%
  • Abdominal Pain
    6%
  • Somnolence
    6%
  • Amnesia
    4%
  • Dysmenorrhea
    4%
  • Paresthesia
    3%
  • Eye pain
    3%
See more detailed side effects
The Remeron (mirtazapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Dependence and withdrawal

    Continuous use for 2 weeks or more

  • Driving impairment

    Alcohol

    ...and 2 more risk factors

  • Abnormal thoughts

    Undiagnosed psychiatric conditions

  • Sleep driving

    Taking with alcohol or drugs

  • Risk to fetus

    Women of childbearing age

    ...and 1 more risk factors

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    Age 24 years or younger

  • Serotonin syndrome

    Using other medications that affect serotonin

  • Heart problems

    History of heart problems

    ...and 2 more risk factors

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings