Compare Sonata vs. Silenor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Helps you sleep.

Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.

2.9/ 5 average rating with 175 reviewsforSonata
Helps you relax, and sleep.

Doxepin is a non-addictive way to help people stay asleep, but it comes with a list of side effects.

Upsides
  • Effective at helping people fall asleep faster.
  • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
  • In a clinical trial Doxepin was able to significantly improve sleep quality.
  • Doxepin helps improve your appetite, energy level, and sense of well-being, which increases your interests.
  • Once your body gets used to Doxepin, most of the side effects go away.
  • Doxepin comes in a generic form, so it is pretty cheap.
  • Doxepin is not addictive.
Downsides
  • Not typically used for long-term treatment since it can be habit-forming.
  • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
  • Interacts badly with many other medications.
  • Not a good option if you're pregnant or breast-feeding.
  • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
  • Some people taking Doxepin walk, drive, eat, and have sex while sleeping. Be sure to tell your doctor if this happens to you.
  • Doxepin can increase your appetite, leading to weight gain.
  • Taking Doxepin can make emptying your bladder difficult.
  • Some people have suicidal thoughts when taking Doxepin.
  • Doxepin can interact with many different medications, vitamins, and alternative treatments.
Used for
  • Alcoholism - Anxiety - Depression Anxiety - Depression Anxiety - Depression - Psychoneurotic personality disorder Insomnia Pruritus (Moderate)
  • Due to atopic dermatitis or lichen simplex chronicus
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
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Reviews
175 reviews so far
42%
saidit'sworth it
23%
saiditworked well
27%
saidit'sa big hassle

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Side effects
18possible side effects
  • Headache
    42%
  • Dizziness
    9%
  • Nausea
    8%
  • Asthenia
    7%
  • Abdominal Pain
    6%
  • Somnolence
    6%
  • Amnesia
    4%
  • Dysmenorrhea
    4%
  • Paresthesia
    3%
  • Eye pain
    3%
  • Malaise
    2%
  • Anorexia
    2%
  • Depersonalization
    2%
  • Hypesthesia
    2%
  • Tremor
    2%
  • Abnormal Vision
    2%
  • Hyperacusis
    2%
  • Parosmia
    2%
See more detailed side effects
The Silenor (Doxepin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Dependence and withdrawal
    • Continuous use for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
    • Less than 7 hours of sleep
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Sleep driving
    • Taking with alcohol or drugs
  • Serious allergic reactions
  • Risk to fetus
    • Women of childbearing age
    • Breast-feeding
See more detailed risks and warnings
No information currently available