Compare Sonata vs. Unisom

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sonata (Zaleplon)

Prescription only
Helps you sleep.

Sonata (Zaleplon) helps you fall asleep, but it's not as good for staying asleep. It also interacts with a lot of diseases and other drugs.

3.8/ 7 average rating with 175 reviewsforSonata
Treats allergy symptoms and helps you sleep.

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

4.5/ 7 average rating with 585 reviewsforUnisom
Upsides
  • Effective at helping people fall asleep faster.
  • Doesn't last as long in the body as some other sleep medicines, so it's okay to take it in the middle of the night as long as you enough time to sleep. (But be sure to discuss it with your doctor first.)
  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
Downsides
  • Not typically used for long-term treatment since it can be habit-forming.
  • Doesn't last as long in the body as other sleep medicines, so it's not as good at helping you stay asleep.
  • Interacts badly with many other medications.
  • Not a good option if you're pregnant or breast-feeding.
  • People have sleep-walked, sleep-driven, and sleep-eaten while on Sonata (Zaleplon).
  • Might not be safe if you have problems with your liver, kidneys, lungs, or if you have a history of depression.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behaviors so you can sleep better naturally.
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
Used for
Dosage forms
  • Pill
  • Pill
  • Chewable tablet
  • Liquid
Price
Lowest price near you
$16.93
Find instant savings
No pricing information available
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at Kroger, Albertsons, Safeway, and other pharmacies.
Reviews
175 
42%
think this treatment is worth it
23%
think this treatment works well
27%
think this treatment is a hassle

Have you used Sonata (Zaleplon)?

Leave a review
585 
58%
think this treatment is worth it
32%
think this treatment works well
11%
think this treatment is a hassle

Have you used Unisom Sleeptabs (Doxylamine)?

Leave a review
Side effects
10possible side effects
  • Headache
    42%
  • Dizziness
    9%
  • Nausea
    8%
  • Asthenia
    7%
  • Abdominal Pain
    6%
  • Somnolence
    6%
  • Amnesia
    4%
  • Dysmenorrhea
    4%
  • Paresthesia
    3%
  • Eye pain
    3%
See more detailed side effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Dependence and withdrawal

    Continuous use for 2 weeks or more

  • Driving impairment

    Alcohol

    ...and 2 more risk factors

  • Abnormal thoughts

    Undiagnosed psychiatric conditions

  • Sleep driving

    Taking with alcohol or drugs

  • Risk to fetus

    Women of childbearing age

    ...and 1 more risk factors

See more detailed risks and warnings
  • Overdosage

    Using other drugs with similar ingredients

  • Increased side effects

    Age 65 years or older

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Hyperactivity

    Children age 6 years or younger

  • Trouble urinating

    Enlarged prostate

    ...and 1 more risk factors

  • Vision changes

    Glaucoma

  • Breastfeeding

    Nursing mothers

See more detailed risks and warnings