Compare Spiriva vs. theophylline

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Makes it easier to breathe. Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.Coming soon.
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Reviews & ratings
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Reviews for Spiriva (Tiotropium)
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Side effects
  • Dry mouth 13%
  • Respiratory tract infection 4%
  • Sore throat 2%
  • Sinus inflammation 2%
  • Urinary tract infection 2%
  • Chest pain (non-specific) 2%
  • Abdominal pain 2%
  • Yeast infection 2%
  • Rash 2%
  • Nosebleed 2%
More Spiriva side effects »

We haven’t found good data for theophylline side effects.

FDA side effect reports for theophylline »
How it works
Spiriva (Tiotropium) is a bronchodilator. It relaxes muscles in your lungs to open your airways and make breathing easier.Coming soon.
Type of medication
Long-acting bronchodilator
Prescription only
Coming soon.
Available as
  • Inhaler
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
  • Asthma Chronic obstructive pulmonary disease Exercise-induced asthma; Prophylaxis Nocturnal asthma
Risk factors for serious side effects
  • History of atropine allergic reaction
    • History of narrow-angle glaucoma
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
    • Severe milk protein allergy
    • History of moderate to severe kidney disease
    • Taking with other anticholinergic medications
    Detailed Spiriva (Tiotropium) risks & warnings »
    Coming soon.
    Pregnancy category
    No specific alcohol-related info.No specific alcohol-related info.
    No specific food-related info.No specific food-related info.
    Kidneys and liver
    • The kidney is mainly responsible for removing Spiriva (Tiotropium) from the body so people with kidney disease or reduced function need to be watched closely. Spiriva (Tiotropium) can build up in the body and cause certain side effects. Tell your doctor if you develop dry mouth, blurry vision, confusion, sweating, increased heart rate or constipation. You may need to discuss other medication options to treat your COPD.
    No specific kidneys and liver-related info.
    No specific sex-related info.No specific sex-related info.
    No specific sleep-related info.No specific sleep-related info.
    No specific weight-related info.No specific weight-related info.
    Upsides and benefits
    • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
    • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
    • You only need to take it once a day.
    Coming soon.
    Downsides and risks
    • Won't cure your COPD (but it will relieve your symptoms).
    • You'll need to use this medicine for a long time, and you have to take it every day.
    • Can make symptoms of enlarged prostate or urinary blockage worse.
    • Can worsen a certain type of glaucoma.
    • You might feel dizzy or have blurry vision while taking this medicine.
    Coming soon.
    Tips from our pharmacists for people taking the medication
    • Don't swallow the capsule. Insert the capsule into an inhaler device only.
    • Use daily to control your COPD.
    • Starts working the first few hours, but it may take longer to feel full effects.
    • Prevents breathing problems, but doesn't stop sudden cough or wheezing once they start.
    • Don't breathe out into the inhaler.
    • You might feel dizzy and notice changes in your vision.
    • Don't use it if you have an allergy to atropine.
    • Contains lactose, so don't use it if you're allergic to milk protein.
    Coming soon.
    Learn more
    More about SpirivaSide effectsReviews & ratingsAlternativesFDA package insert
    More about theophyllineSide effectsReviews & ratingsFDA package insert