Compare Strattera vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Strattera
(Atomoxetine)

Dexedrine
(Dextroamphetamine)

Helps you focus and stay alert. Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.Helps you stay awake and focus. Dexedrine (Dextroamphetamine) is an effective and cheap medication used to treat ADHD, but it can be habit-forming and is not used for long-term treatment.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.32Strattera
Reviews for Strattera
46%
of people (All ages) say Strattera is worth it
32%
say it works well
24%
say it's a big hassle
Have you used Strattera (Atomoxetine)?
Worth itNot sureNot worth it
Reviews for Dexedrine
89%
-43% worse vs. Strattera
79%
-47% worse vs. Strattera
21%
-3% worse vs. Strattera
Have you used Dexedrine (Dextroamphetamine)?
Worth itNot sureNot worth it
Side effects
StratteraDexedrine
  • Therapeutic response unexpected 1%
  • Rash 1%
  • Any side effect 2%
  • Weight loss 3%
  • Anorexia 2%
  • Dizziness 3%
  • Irritability 3%
  • Fatigue 5%
  • Changes in heart rate or blood pressure 10%
  • Nausea 5%
More Strattera side effects »

We haven’t found good data for Dexedrine side effects.

FDA side effect reports for Dexedrine »
How it works
StratteraDexedrine
Strattera (Atomoxetine) is a norepinephrine reuptake inhibitor (non-stimulant). Researchers don't know exactly how it works for ADHD, but it increases norepinephrine activity in the brain, which affects attention and behavior.Dexedrine (Dextroamphetamine) is a stimulant. It treats narcolepsy and attention-deficit/hyperactivity disorder (ADHD) by increasing norepinephrine and dopamine activity in the brain.
Type of medication
StratteraDexedrine
Prescription onlyLower-cost generic availablePrescription onlyLower-cost generic available
Available as
StratteraDexedrine
  • Pill
  • Pill
  • Extended release
  • Liquid
Used for
StratteraDexedrine
Risk factors for serious side effects
StratteraDexedrine
  • Age below 18
  • History of heart problems
  • History of psychotic episodes
  • History of Bipolar Disorder
  • Starting Strattera (Atomoxetine) before puberty
Detailed Strattera (Atomoxetine) risks & warnings »
  • History of heart problems
  • History of drug abuse
  • History of psychotic episodes
  • History of bipolar disorder
  • Children
Detailed Dexedrine (Dextroamphetamine) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Upsides and benefits
StratteraDexedrine
  • One of the few medications used to treat ADHD that's not a stimulant.
  • It isn't a controlled substance.
  • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
  • You usually only need to take it once a day.
  • Recommended as a first-choice medication to treat ADHD in both adults and children.
  • Available as a generic, so it is cheaper than other medications used to treat ADHD.
  • Available in an immediate release and extended release form, which allows for once or twice a day dosing.
Downsides and risks
StratteraDexedrine
  • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
  • It's only available as a brand name medication, so it can be expensive.
  • Fruit juice lowers the amount of Dexedrine (Dextroamphetamine) that gets into your body.
  • If you want to stop taking Dexedrine (Dextroamphetamine), you have to talk to your doctor since stopping cold turkey can cause withdrawal symptoms.
  • Dexedrine (Dextroamphetamine) is usually not used long-term since it can be habit-forming.
Tips from our pharmacists for people taking the medication
StratteraDexedrine
  • It can cause changes in sex drive.
  • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
  • It can also cause changes in your mood.
  • Take it at the same time every day.
  • Common side effects include decreased appetite, nausea, and constipation.
  • The capsules can't be opened and need to be swallowed whole.
  • Take your last dose before early afternoon, otherwise you won't be able to sleep.
  • Don't take with fruit juice or vitamin C, because they'll lower the amount of Dexedrine (Dextroamphetamine) that gets into your body.
  • Can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
  • If you've been taking Dexedrine (Dextroamphetamine) for a while and decide to stop it, you'll experience withdrawal symptoms if you stop it too fast.
  • Can cause reduced appetite, insomnia, and restlessness.
Learn more
More about StratteraSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Strattera (Atomoxetine)?
Worth itNot sureNot worth it
More about DexedrineSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dexedrine (Dextroamphetamine)?
Worth itNot sureNot worth it