Compare Strattera vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Strattera
(Atomoxetine)

Dexedrine
(Dextroamphetamine)

Helps you focus and stay alert. Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.Helps you stay awake and focus. Dexedrine (Dextroamphetamine) is an effective and cheap medication used to treat ADHD, but it can be habit-forming and is not used for long-term treatment.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.275862068965517Strattera
Reviews for Strattera (Atomoxetine)
45%
of people say Strattera (Atomoxetine) is worth it
32%
say it works well
25%
say it's a big hassle
Reviews for Dexedrine (Dextroamphetamine)
90%
+45% vs. Strattera (Atomoxetine)
76%
+44% vs. Strattera (Atomoxetine)
24%
+1% vs. Strattera (Atomoxetine)
Side effects
StratteraDexedrine
  • Nausea 20%
  • Dry mouth 15%
  • Decreased appetite 13%
  • Abdominal pain 8%
  • Drowsiness 7%
  • Impotence 7%
  • Sleep difficulty 7%
  • Dizziness 5%
  • Constipation 5%
  • Difficulty with urination flow 5%
More Strattera side effects »

We haven’t found good data for Dexedrine side effects.

FDA side effect reports for Dexedrine »
How it works
StratteraDexedrine
Strattera (Atomoxetine) is a norepinephrine reuptake inhibitor (non-stimulant). Researchers don't know exactly how it works for ADHD, but it increases norepinephrine activity in the brain, which affects attention and behavior.Dexedrine (Dextroamphetamine) is a stimulant. It treats narcolepsy and attention-deficit/hyperactivity disorder (ADHD) by increasing norepinephrine and dopamine activity in the brain.
Type of medication
StratteraDexedrine
Selective norepinephrine reuptake inhibitor (SNRI)Prescription only
StimulantPrescription only
Available as
StratteraDexedrine
  • Pill
  • Pill
  • Extended release
  • Liquid
Used for (click to learn more)
StratteraDexedrine
Risk factors for serious side effects
StratteraDexedrine
  • Age below 18
    • History of heart problems
    • History of psychotic episodes
    • History of Bipolar Disorder
        • Starting Strattera (Atomoxetine) before puberty
        Detailed Strattera (Atomoxetine) risks & warnings »
        • History of heart problems
        • History of drug abuse
        • History of psychotic episodes
        • History of bipolar disorder
        • Children
        • History of seizures
        • Women of childbearing age
        • Breastfeeding
        • Use of MAO inhibitors
        Detailed Dexedrine (Dextroamphetamine) risks & warnings »
        Pregnancy category
        StratteraDexedrine
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        CFDA pregnancy category (Weigh risks vs. benefits)

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        See the FDA package insert
        Alcohol
        No specific alcohol-related info.No specific alcohol-related info.
        Food
        No specific food-related info.No specific food-related info.
        Kidneys and liver
        No specific kidneys and liver-related info.No specific kidneys and liver-related info.
        Sex
        • It can cause changes in sex drive.
        • There have been reports of men having an erection lasting more than 4 hours while on Strattera (Atomoxetine). This has been rare. If not treated in time, this can cause permanent damage to your penis, including impotence. Talk to your doctor immediately or go to the emergency room if this happens.
        No specific sex-related info.
        Sleep
        No specific sleep-related info.
        • Take your last dose before early afternoon, otherwise you won't be able to sleep.
        Weight
        • Appetite suppression may occur. In clinical studies, long-term treatment with stimulants similar to Strattera (Atomoxetine) caused a temporary slowing of growth rate (both height and weight) in children who started the medication before they started puberty. Doctors should monitor children's growth during treatment.
        • Appetite suppression can occur. In clinical studies, long-term treatment with stimulants similar to Dexedrine (Dextroamphetamine) caused a temporary slowing of growth rate (both height and weight) in children who started the medication before they started puberty. Doctors should monitor children's growth during treatment.
        Upsides and benefits
        StratteraDexedrine
        • One of the few medications used to treat ADHD that's not a stimulant.
        • It isn't a controlled substance.
        • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
        • You usually only need to take it once a day.
        • Recommended as a first-choice medication to treat ADHD in both adults and children.
        • Available as a generic, so it is cheaper than other medications used to treat ADHD.
        • Available in an immediate release and extended release form, which allows for once or twice a day dosing.
        Downsides and risks
        StratteraDexedrine
        • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
        • It's only available as a brand name medication, so it can be expensive.
        • Fruit juice lowers the amount of Dexedrine (Dextroamphetamine) that gets into your body.
        • If you want to stop taking Dexedrine (Dextroamphetamine), you have to talk to your doctor since stopping cold turkey can cause withdrawal symptoms.
        • Dexedrine (Dextroamphetamine) is usually not used long-term since it can be habit-forming.
        Tips from our pharmacists for people taking the medication
        StratteraDexedrine
        • It can cause changes in sex drive.
        • Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
        • It can also cause changes in your mood.
        • Take it at the same time every day.
        • Common side effects include decreased appetite, nausea, and constipation.
        • The capsules can't be opened and need to be swallowed whole.
        • Take your last dose before early afternoon, otherwise you won't be able to sleep.
        • Don't take with fruit juice or vitamin C, because they'll lower the amount of Dexedrine (Dextroamphetamine) that gets into your body.
        • Can affect your concentration, so don't drive or do anything that requires concentration until you know how your body reacts to it.
        • If you've been taking Dexedrine (Dextroamphetamine) for a while and decide to stop it, you'll experience withdrawal symptoms if you stop it too fast.
        • Can cause reduced appetite, insomnia, and restlessness.
        Learn more
        More about StratteraSide effectsReviews & ratingsAlternativesFDA package insert
        More about DexedrineSide effectsReviews & ratingsAlternativesFDA package insert