Helps you focus and stay alert. Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.
Treats ADHD and lowers blood pressure. Clonidine is a non-stimulant option to manage ADHD symptoms and behaviors, but it can lower your blood pressure.
How it works
Strattera (Atomoxetine) is a norepinephrine reuptake inhibitor (non-stimulant). Researchers don't know exactly how it works for ADHD, but it increases norepinephrine activity in the brain, which affects attention and behavior.
Clonidine is an alpha-2 agonist. Researchers don't know exactly how it works for ADHD. It works in the brain and lowers the activity of certain stress hormones, but it's not a stimulant like many ADHD medicines.
Type of medication
Selective norepinephrine reuptake inhibitor (SNRI)Prescription only
› There have been reports of men having an erection lasting more than 4 hours while on Strattera (Atomoxetine). This has been rare. If not treated in time, this can cause permanent damage to your penis, including impotence. Talk to your doctor immediately or go to the emergency room if this happens.
No specific sex-related info.
No specific sleep-related info.
No specific sleep-related info.
› Appetite suppression may occur. In clinical studies, long-term treatment with stimulants similar to Strattera (Atomoxetine) caused a temporary slowing of growth rate (both height and weight) in children who started the medication before they started puberty. Doctors should monitor children's growth during treatment.
No specific weight-related info.
Upsides and benefits
› One of the few medications used to treat ADHD that's not a stimulant.
› It isn't a controlled substance.
› Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
› You usually only need to take it once a day.
› Can be used alone or together with a stimulant-type medicine to treat ADHD.
› In studies, it improved attention span and lowered hyperactivity and impulsivity in children and adolescents ages 6 to 17.
› Also treats blood pressure and some nervous system and psychiatric conditions.
Downsides and risks
› It's a second-line medication used to treat ADHD. Other medications are usually tried first.
› It's only available as a brand name medication, so it can be expensive.
› Can lower blood pressure.
› The pill form can make some people sleepy, dizzy, and have dry mouth.
› You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Tips from our pharmacists for people taking the medication
› It can cause changes in sex drive.
› Can raise your blood pressure and pulse, so it's not safe for people with heart problems.
› It can also cause changes in your mood.
› Take it at the same time every day.
› Common side effects include decreased appetite, nausea, and constipation.
› The capsules can't be opened and need to be swallowed whole.
› Can cause drowsiness, headache, dizziness, and dry mouth.
› For ADHD: Might take up to 2 weeks to see effects.
› For high blood pressure: Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
› If side effects don't go away, talk to your doctor about alternatives.