Compare Strattera vs. Vyvanse

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Strattera (Atomoxetine)

Prescription only
Helps you focus and stay alert.

Strattera (Atomoxetine) isn't considered a first-line medication for ADHD, but since it isn't a stimulant, it's still highly recommended.

3.2/ 5 average rating with 94 reviewsforStrattera
Helps you focus and stay alert.

Vyvanse (lisdexamfetamine) is a first-choice treatment for attention-deficit/hyperactivity disorder, but it can be expensive since it's only available as a brand name product.

3.7/ 5 average rating with 491 reviewsforVyvanse
Upsides
  • One of the few medications used to treat ADHD that's not a stimulant.
  • It isn't a controlled substance.
  • Strattera (Atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
  • You usually only need to take it once a day.
  • Vyvanse (lisdexamfetamine) is a first-choice medication to treat attention-deficit/hyperactivity disorder (ADHD).
  • It is usually dosed once a day, so parents don't need to send the medication with their children to school.
  • Can take the capsule as a whole or mix the contents with water, orange juice, or yogurt.
  • Available as a chewable pill form.
Downsides
  • It's a second-line medication used to treat ADHD. Other medications are usually tried first.
  • It's only available as a brand name medication, so it can be expensive.
  • Need to take Vyvanse (lisdexamfetamine) in the morning, otherwise it can cause difficulty sleeping at night.
  • Vyvanse (lisdexamfetamine) is not available as a generic medication, so it is expensive.
  • This medicine has the potential for abuse and dependence.
  • Can cause serious side effects for the heart.
  • Can also slow growth in children and cause weight loss.
Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
94 reviews so far
46%
saidit'sworth it
32%
saiditworked well
24%
saidit'sa big hassle

Have you used Strattera (Atomoxetine)?

Leave a review
491 reviews so far
67%
saidit'sworth it
49%
saiditworked well
17%
saidit'sa big hassle

Have you used Vyvanse (lisdexamfetamine)?

Leave a review
Side effects
30possible side effects
  • Nausea
    26%
  • Dry mouth
    20%
  • Decreased appetite
    16%
  • Insomnia
    15%
  • Changes in heart rate or blood pressure
    10%
  • Fatigue
    10%
  • Constipation
    8%
  • Dizziness
    8%
  • Somnolence
    8%
  • Erectile dysfunction
    8%
  • Abdominal pain
    7%
  • Urinary hesitation
    6%
  • Irritability
    5%
  • Dyspepsia
    4%
  • Vomiting
    4%
  • Abnormal dreams
    4%
  • Ejaculation delayed and/or ejaculation disorder
    4%
  • Hyperhidrosis
    4%
  • Palpitations
    3%
  • Chills
    3%
  • Paraesthesia
    3%
  • Libido decreased
    3%
  • Sleep disorder
    3%
  • Dysmenhorrhea
    3%
  • Hot flush
    3%
  • Feeling jittery
    2%
  • Thirst
    2%
  • Weight loss
    2%
  • Dysuria
    2%
  • Any sexual side effect
    2%
See more detailed side effects
15possible side effects
  • Decreased appetite
    27%
  • Difficulty sleeping
    27%
  • Dry mouth
    26%
  • Diarrhea
    7%
  • Nausea
    7%
  • Anxiety
    6%
  • Loss of appetite
    5%
  • Feeling jittery
    4%
  • Agitation
    3%
  • Increased blood pressure
    3%
  • Sweating
    3%
  • Restlessness
    3%
  • Difficulty breathing
    2%
  • Increased heart rate
    2%
  • Tremor
    2%
See more detailed side effects
Risks and risk factors
  • Suicidal thinking
    • Age below 18
  • Liver disease
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of Bipolar Disorder
  • Prolonged erection
  • Problems with urination
  • Long-term growth suppression
    • Starting Strattera (Atomoxetine) before puberty
See more detailed risks and warnings
  • High blood pressure
    • Taking monoamine oxidase inhibitors (MAOI) 14 days before starting Vyvanse (lisdexamfetamine)
  • Abuse and dependence
    • History of drug abuse
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Long-term growth suppression
    • Children ages 6 to 12
See more detailed risks and warnings