Compare Stribild vs. Isentress

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)

Prescription only

Isentress (raltegravir)

Prescription only
Treats HIV infection.

Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication and one of the first choices used to treat HIV infections.

Works with other medicications to treat HIV infection.

Isentress (raltegravir) is considered a first choice to be used with other medications for treating HIV, but it can have more side effects than other similar medicines.

Upsides
  • First-choice treatment for HIV in patients with good kidney function.
  • One tablet contains four different HIV medications.
  • Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is only taken once daily.
  • There are assistance programs available through the manufacturer of Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) if you need help paying for high insurance copays.
  • Isentress (raltegravir) is a first choice treatment to use together with other medications to treat HIV.
  • If you have difficulty swallowing the tablet, there is a chewable tablet or oral suspension available.
  • Can be used by children 4 weeks and older.
  • People with mild to moderate kidney or liver damage can use Isentress (raltegravir).
Downsides
  • Can't be used in patients with kidney problems.
  • Can interact with many other drugs.
  • It might be hard to remember to take Isentress (raltegravir) two times a day. Other similar medicines are once a day.
  • The chewable tablets contain phenylalanine and should be avoided in people who have phenylketonuria.
  • Isentress (raltegravir) cannot be used alone to treat or prevent HIV. It must be used together with other medications.
  • Not available as part of a combination tablet, so you'll have to take more tablets daily compared to other combinations.
Used for
Dosage forms
  • Pill
  • Pill
  • Chewable tablet
  • Liquid
Price
Lowest price near you
$3158.78
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Lowest price near you
$1424.38
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Reviews
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Side effects
9possible side effects
  • Nausea
    16%
  • Diarrhea
    12%
  • Abnormal dreams
    9%
  • Headache
    7%
  • Fatigue
    4%
  • Rash
    4%
  • Dizziness
    3%
  • Insomnia
    3%
  • Flatulence
    2%
See more detailed side effects
5possible side effects
  • Headache
    4%
  • Insomnia
    4%
  • Nausea
    3%
  • Fatigue
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and warnings
  • Lactic acidosis | Enlarged, fatty liver

    Liver disease

    ...and 2 more risk factors

  • Cannot be used to treat Hepatitis B Virus (HBV)

    Hepatitis B Virus infection

  • Decreased bone mineral density

    History of bone fractures

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 1 more risk factors

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

  • Drug interactions

    Taking medicines that interact with Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)

See more detailed risks and warnings
  • Severe skin reactions

    Prior severe allergic reaction to Isentress

  • Allergic reactions

    Prior severe allergic reaction to Isentress

  • Rhabdomyolysis (Muscle damage)

    Concurrent use of other drugs which can cause muscle pain/damage

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

See more detailed risks and warnings